Results 201 to 210 of about 5,550,853 (286)

Adherence to Protocol Registration Among Systematic Reviews on Photobiomodulation: A Meta-Research Study. [PDF]

J Eval Clin Pract
Santos GM, Lopes GCM, Martins Sá KM, da Rocha Soares GA, Gonçalves MLL, Bussadori SK, Santos EM, Martimbianco ALC.   +7 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Intention-to-treat and per-protocol analysis [PDF]

CMAJ, 2011
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A comparative analysis and critical review of two rTMS treatment durations in dogs with drug-resistant idiopathic epilepsy. [PDF]

BMC Vet Res
Hünting D, Meller S, Twele F, Meyerhoff N, Bhatti SFM, Volk HA, Charalambous M.   +6 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Design characteristics of sequential multiple assignment randomised trials (SMARTs) for human health: a scoping review of studies between 2009 and 2024. [PDF]

BMJ Open
Freeman NLB, Browder SE, Rowland B, Jones EP, Hoch M, Kim A, Zhou CW, Kahkoska AR, McGinigle KL, Ivanova A, Kosorok MR, Anstrom KJ.   +11 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

High-flow nasal cannula use for respiratory support in children for indications other than acute bronchiolitis. [PDF]

Cochrane Database Syst Rev
El-Khatib M, El Bcherawi N, Atallah F, Moukarzel M, HajAli T, Khabsa J, Moukalled H, Sibai L, Maroun P, Raphael C.   +9 more
europepmc   +1 more source

Gap analysis - existing protocols

D2.3: Deliverables for the gap analysis of protocols•A comprehensive and complete list of current refuelling protocols on the market•An analysis of boundary conditions used for the development of the current refuelling protocols, including their nature, justification and impact on the refuelling protocol performance and cost of the refuelling ...
openaire   +1 more source