Results 151 to 160 of about 3,297,271 (264)

Implementation of Self-Initiated Event-Contingent Ecological Momentary Assessment for Environmental Exposures: Prospective Observational Study. [PDF]

JMIR Form Res
Neely G, Ström I.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Proximity Labeling in <i>Caenorhabditis elegans</i> to Detect Neuronal Proteins During Memory Formation. [PDF]

Bio Protoc
Rahmani A, Chew YL.
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Randomized controlled trial comparing 7-day fexuprazan-based and 14-day rabeprazole-based triple therapies for Helicobacter pylori eradication. [PDF]

Medicine (Baltimore)
Kim JH, Nam SJ, Kim SH, Lee JH, Lee SH, Lee SJ, Park SC.   +6 more
europepmc   +1 more source

Consumption of dairy foods and diabetes incidence: a dose-response meta-analysis of observational studies.

American Journal of Clinical Nutrition, 2016
L. Gijsbers, Eric L. Ding, Vasanti S. Malik, J. de Goede, J. Geleijnse, S. Soedamah-Muthu   +5 more
semanticscholar   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Discordance between early mobility protocol expectations and nurse-led mobilizations of critically ill children: A quality improvement initiative. [PDF]

World J Crit Care Med
Manikandan D, Lenker H, Mennie C, Morgenstern S, Furniturewala S, Hwang L, Hajnik K, Brown KM, Shilkofski N, Kudchadkar SR, LaRosa JM.   +10 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

The Dissemination of Standardised Care Protocol Guidelines for High-Risk Emergency Abdominal Surgery Patients in Denmark. [PDF]

Acta Anaesthesiol Scand
Gjørup IVF, Wildgaard K, Burcharth J, Vester-Andersen M.   +3 more
europepmc   +1 more source