Results 211 to 220 of about 3,297,271 (264)

Nonoperative treatment of Achilles tendon rupture with 6- versus 8-week protocol: a single-center cohort study from Finland. [PDF]

Acta Orthop
Happonen V, Koivisto A, Härkönen A, Kröger H.   +3 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A Mobilisation Protocol in the Management of Posterior Foetal Presentations: A Multicentre Observational Pilot Study. [PDF]

Healthcare (Basel)
Conesa-Ferrer MB, Martínez-Sandoval MJ, López-Martínez EM, Vera-Pérez JA, Baño-Piñero I.   +4 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Protocol of a single-arm open-label pilot study of extended rTMS therapy for treatment-resistant depression (ExTMS study). [PDF]

PCN Rep
Takahashi S, Eto M, Hata M, Shinosaki K, Ikeda M.   +4 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Randomised treatment of acute pancreatitis with infliximab: protocol for a double-blind, placebo-controlled, multi-centre, adaptive, phase 2 superiority trial (RAPID-I). [PDF]

BMJ Open
Lin J, Smyth M, Spowart C, Brown M, Powell I, Latawiec D, Wu D, Huang W, Mukherjee R, Szatmary P, Baron R, Dunne D, Evans J, Srinivas S, Bond-Smith G, Cooper J, Smith A, Manzelli A, Elkhodair S, O'Reilly D, Mitra V, Body R, Siriwardena AK, Subramanian S, Plumpton C, Hughes DA, Mclaren T, Lucas A, Gamble C, Jaki T, Sutton R.   +30 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source