The Blood-Brain and Other Neural Barriers - Reviews and Protocols,Humana Press, Springer Science and Business Media [PDF]
David J. Begley
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Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Study protocol of “From Science 2 School”—prevalence of sports and physical exercise linked to omnivorous, vegetarian and vegan, diets among Austrian secondary schools [PDF]
Katharina Wirnitzer+8 more
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Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Bridging behavior science and gaming theory: Using the Intervention Mapping Protocol to design a serious game against cyberbullying [PDF]
Ann DeSmet+10 more
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We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Chronic pain self-management support with pain science education and exercise (COMMENCE): study protocol for a randomized controlled trial [PDF]
Jordan Miller+3 more
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A mixed-methods study on the design of Artificial Intelligence and data science-based strategies to inform public health responses to COVID-19 in different local health ecosystems: A study protocol for COLEV [PDF]
Catalina González-Uribe+12 more
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This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
Background Open science emphasizes the free and accessible dissemination of scholarly outputs to a wide audience, including scientists, stakeholders, and the general public. Its core principle is the open sharing of knowledge to enable reuse, replication,
Jon Sampedro+4 more
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