Results 171 to 180 of about 7,056,691 (346)
The Museum as a Mindful Space: Reducing Visitors' Stress and Anxiety Levels Through the ASBA Protocol. [PDF]
Banzi A +3 more
europepmc +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Informationally complete distributed metrology without a shared reference frame. [PDF]
Xu HQ +8 more
europepmc +1 more source
More on the Science Commons open data protocol
Thinh Nguyen, Freedom to Research: Keeping Scientific Data Open, Accessible, and Interoperable, <em> Science Commons </em> , April 23, 2008. (Thanks to the Science Commons blog.) Nguyen is the Counsel for Science Commons.
openaire +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Protocol, mainstreaming Open Science
Protocol for baselining and bestpractice assessment of Mainstreaming Open Science ...
openaire +1 more source
MOUSS protocol for the Pacific Islands Fisheries Science Center
Dianna R. Miller-Greene +2 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source

