Results 231 to 240 of about 3,341,855 (333)

Structural models for spreading and scaling digital health initiatives: A scoping review protocol. [PDF]

PLoS One
Laur C, Lee K, Milat A, Petrie S, Ladak Z, Lui V, Hall A, Nathan N, Medeiros P, Ivers N, Bhattacharyya O.   +10 more
europepmc   +1 more source

«Suivre un protocole» : une pratique pour apprendre la science ?

Le réseau des LéA, 2022
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Reply to Fernández-Quevedo García et al.: Surface tension in phase-separated active Brownian particles. [PDF]

Proc Natl Acad Sci U S A
Li L, Sun Z, Yang M.
europepmc   +1 more source

Safety protocols for citizen science demonstrations

Safety protocols for citizen science demonstrations (M6, METNO)
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Acute effects of post-activation performance enhancement on half-squat training volume and repetition performance in strength-train men: a randomised crossover study. [PDF]

BMC Sports Sci Med Rehabil
Pancar Z, İlhan MT, Karaday E, Karaca B, Pardos EM, Praça GM, Carneiro L, Nobari H.   +7 more
europepmc   +1 more source

Current Protocols in Protein Science

, 2018
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Post-hospital physical rehabilitation for physical function recovery among community-dwelling survivors of critical illness: A systematic review protocol. [PDF]

PLoS One
Farley C, Newman ANL, Caron C, Honarmand K, Phillips SM, Smith-Turchyn J, Brooks D.   +6 more
europepmc   +1 more source