Results 271 to 280 of about 8,627,478 (377)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Correction: Nadarajan et al. Development, Management and Utilization of a Kiwifruit (<i>Actinidia</i> spp.) In Vitro Collection: A New Zealand Perspective. <i>Plants</i> 2023, <i>12</i>, 2009. [PDF]

Plants (Basel)
Nadarajan J, Esfandiari A, Mathew L, Divinagracia J, Wiedow C, Morgan E.   +5 more
europepmc   +1 more source

National Football League Head, Neck and Spine Committee’s Concussion Diagnosis and Management Protocol: 2017-18 season

British Journal of Sports Medicine, 2018
R. Ellenbogen, H. Batjer, Javier Cárdenas, M. Berger, J. Bailes, Elizabeth M. Pieroth, R. Heyer, N. Theodore, W. Hsu, Elizabeth Nabel, J. Maroon, R. Cantu, R. Barnes, James Collins, M. Putukian, R. Lonser, G. Solomon, Allen K. Sills   +17 more
semanticscholar   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Case Report: Treating Atrial Fibrillation with the Neubie Direct Current Electrical Stimulation. [PDF]

Med Devices (Auckl)
Ennis R, Husted C.
europepmc   +1 more source

DEVELOPMENT OF LEADERSHIP SKILLS IN MEDICAL EDUCATION: A SCOPING REVIEW PROTOCOL. Abstract Background: Leadership is recognized as an essential competency in health care and science, being central for professionals to face health challenges. Few physicians feel prepared to serve as leaders in the health care environment, and few receive training in the leadership skills needed to be successful. Teaching leadership skills together with extensive longitudinal clinical education in an authentic … [PDF]

Eliana Fazuoli Chubaci, Carlos Dario da Silva Costa, Martins Fideles dos Santos Neto, Emerson Roberto dos Santos, Ana Maria Rita Pedroso Vilela Torres de Carvalho Engel, Ana Caroline dos Santos Costa, Taísa Morete da Silva, Helena Landim Gonçalves Cristóvão, Alex Bertolazzo Quitério, Alba Regina de Abreu Lima, Vânia Maria Sabadoto Brienze, Fernando Nestor Fácio, Júlio Cesar André   +12 more
openalex   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Rh-catalyzed enantioselective hydrosilylation of unactivated alkenes. [PDF]

Chem Sci
Wu Y, Qian HY, Zhang H, Zou JY, Wu QY, Nie XX, Zheng L, Peng Q, Wang P.   +8 more
europepmc   +1 more source

Leveraging data science and machine learning for urban climate adaptation in two major African cities: a HE²AT Center study protocol [PDF]

Christopher Jack, Craig Parker, Yao Etienne Kouakou, Bonnie R. Joubert, Kimberly A. McAllister, Maliha Ilias, Gloria Maimela, Matthew Chersich, Sibusisiwe Makhanya, Stanley Lüchters, Prestige Tatenda Makanga, Etienne Vos, Kristie L. Ebi, Brama Koné, Akbar K. Waljee, Guéladio Cissé   +15 more
openalex   +1 more source