Results 41 to 50 of about 6,953,213 (308)
Identifying the domains of context important to implementation science: a study protocol
Implementation Science, 2015 BackgroundThere is growing recognition that “context” can and does modify the effects of implementation interventions aimed at increasing healthcare professionals’ use of research evidence in clinical practice.
J. Squires +14 more
semanticscholar +1 more source
Carnap’s Turn to the Thing Language
Philosophia Scientiæ, 2018 Rudolf Carnap’s contributions to the Paris 1935 Congress for scientific philosophy signal three important changes in his philosophy: his semantic turn; what would later be called the “liberalization of empiricism”; and his adoption of the so-called thing
Ansten Klev
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
BMC Medical Education, 2023 Background The brand-new anti-choking devices (LifeVac® and DeCHOKER®) have been recently developed to treat Foreign Body Airway Obstruction (FBAO).
Borja Cardalda-Serantes +4 more
doaj +1 more source
A Discrete and Bounded Envy-Free Cake Cutting Protocol for Any Number of Agents [PDF]
IEEE Annual Symposium on Foundations of Computer Science, 2016 We consider the well-studied cake cutting problem in which the goal is to find an envy-free allocation based on queries from n agents. The problem has received attention in computer science, mathematics, and economics.
H. Aziz, Simon Mackenzie
semanticscholar +1 more source
Mouse Anesthesia: The Art and Science
ILAR journal, 2021 There is an art and science to performing mouse anesthesia, which is a significant component to animal research. Frequently, anesthesia is one vital step of many over the course of a research project spanning weeks, months, or beyond.
Kaela Navarro +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Implementation Science, 2018 BackgroundHealth research is conducted with the expectation that it advances knowledge and eventually translates into improved health systems and population health.
I. Graham +26 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source