Results 61 to 70 of about 6,953,213 (308)

Characterising processes and outcomes of tailoring implementation strategies in healthcare: a protocol for a scoping review [version 2; peer review: 2 approved, 1 approved with reservations]

HRB Open Research, 2022
Background: Tailoring strategies to target the salient barriers to and enablers of implementation is considered a critical step in supporting successful delivery of evidence based interventions in healthcare.
Bianca Albers, Sheena M. McHugh, Nickola Pallin, Lauren Clack, Claire Kerins, Eimear Morrissey, Geoffrey M. Curran, Justin Presseau, Byron J. Powell, Cara C. Lewis, Fiona Riordan, Luke Wolfenden   +11 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Open Science Practices in Integrated Assessment Models [version 2; peer review: 2 approved, 1 approved with reservations]

Open Research Europe
Background Open science emphasizes the free and accessible dissemination of scholarly outputs to a wide audience, including scientists, stakeholders, and the general public. Its core principle is the open sharing of knowledge to enable reuse, replication,
Jon Sampedro, Clàudia Rodés-Bachs, Francesco Gardumi, Natasha Frilingou, Camilla Lo Giudice   +4 more
doaj   +1 more source

Developing a Microanalytic Selfregulated Learning Assessment Protocol for Biomedical Science Learning [PDF]

Strides in Development of Medical Education, 2017
Background & Objective: Selfregulated learning (SRL) is highly task and context dependent Microanalytic assessment method measures students SRL processes while performing a particular learning task The present study aimed to design a microanalytic SRL ...
Roghayeh Gandomkar, Azim Mirzazadeh, Ladan Fata, Azim Mirzazadeh, Mohammad Jalili, Kamran Yazdani, Gholamreza Hassanzadeh, John Sandars   +7 more
doaj  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Implementation of IoT-based STEM-Contextual learning with the MQTT protocol on the digital literacy skills of pre-service science teacher

LUMAT
The Internet of Things (IoT) with the Message Queue Telemetry Transport (MQTT) protocol in learning processes is one of the learning innovations in the digital era which has a significant role in students' digital literacy skills.
Didik Setyawarno, Dadan Rosana, Ibrohim, Erti Hamimi, Ade Gafar Abdulloh   +4 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Why emerging leaders should focus on being good postdoctoral supervisors

FEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski, Clara Oudenaarden, Miao Tian, Diyavarshini Gopaul, Anita Kurilla, Pelin Gülizar Ersan   +5 more
wiley   +1 more source

OMIP contribution to CMIP6: experimental and diagnostic protocol for the physical component of the Ocean Model Intercomparison Project

, 2016
The Ocean Model Intercomparison Project (OMIP) is an endorsed project in the Coupled Model Intercomparison Project Phase 6 (CMIP6). OMIP addresses CMIP6 science questions, investigating the origins and consequences of systematic model biases.
S. Griffies, G. Danabasoglu, P. Durack, A. Adcroft, V. Balaji, C. Böning, E. Chassignet, E. Curchitser, J. Deshayes, H. Drange, B. Fox‐Kemper, P. Gleckler, J. Gregory, H. Haak, R. Hallberg, P. Heimbach, H. Hewitt, D. Holland, T. Ilyina, J. Jungclaus, Y. Komuro, J. Krasting, W. Large, S. Marsland, S. Masina, T. McDougall, A. Nurser, J. Orr, A. Pirani, F. Qiao, R. Stouffer, K. Taylor, A. Treguier, H. Tsujino, P. Uotila, M. Valdivieso, Qiang Wang, M. Winton, S. Yeager   +38 more
semanticscholar   +1 more source