Results 71 to 80 of about 3,285,429 (341)

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Nanoscale magnetometry using a single spin system in diamond

, 2011
We propose a protocol to estimate magnetic fields using a single nitrogen-vacancy (N-V) center in diamond, where the estimate precision scales inversely with time, ~1/T$, rather than the square-root of time.
Berry, D. W., Said, R. S., Twamley, J.
core   +1 more source

A survey of researchers’ methods sharing practices and priorities [PDF]

PeerJ
Missing or inaccessible information about the methods used in scientific research slows the pace of discovery and hampers reproducibility. Yet little is known about how, why, and under what conditions researchers share detailed methods information, or ...
Marcel LaFlamme, James Harney, Iain Hrynaszkiewicz   +2 more
doaj   +2 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

MicroMundo Upside Down: Targeted Searching for Antibiotics-Producing Bacteria From Soil With Reverse Antibiosis Approaches

Frontiers in Microbiology, 2020
Tiny Earth (TE) is a popular international citizen science program aimed at improving public awareness on the growing antimicrobial resistance problem of which MicroMundo Albacete is a Spanish node.
María Alvarado, María Alvarado, Pilar Clemente-Casares, Pilar Clemente-Casares, Diego A. Moreno, Diego A. Moreno, Piet W. J. de Groot, Piet W. J. de Groot, Piet W. J. de Groot, Piet W. J. de Groot   +9 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Developing a Microanalytic Selfregulated Learning Assessment Protocol for Biomedical Science Learning [PDF]

Strides in Development of Medical Education, 2017
Background & Objective: Selfregulated learning (SRL) is highly task and context dependent Microanalytic assessment method measures students SRL processes while performing a particular learning task The present study aimed to design a microanalytic SRL ...
Roghayeh Gandomkar, Azim Mirzazadeh, Ladan Fata, Azim Mirzazadeh, Mohammad Jalili, Kamran Yazdani, Gholamreza Hassanzadeh, John Sandars   +7 more
doaj  

A methodological protocol for Annex i Habitats monitoring: The contribution of vegetation science [PDF]

, 2016
The methodological foundations of the recently published Manual for Annex I Habitats monitoring in Italy, edited by the Italian Institute for Environmental Protection and Research (ISPRA) with the scientific support of the Italian Society for Vegetation Science (SISV), are here presented, discussed and related to the most consolidated and acknowledged ...
Gigante, D., Attorre, F., Venanzoni, R., Acosta, A. T. R., Agrillo, E., Aleffi, M., Alessi, N., Allegrezza, M., Angelini, P., Angiolini, C., Assini, S., Azzella, M. M., Bagella, S., Biondi, E., Bolpagni, R., Bonari, G., Bracco, F., Brullo, S., Buffa, G., Carli, E., Caruso, G., Casavecchia, S., Casella, L., Cerabolini, B. E. L., Ciaschetti, G., Copiz, R., Cutini, M., Del Vecchio, S., Del Vico, E., Di Martino, L., Facioni, L., Fanelli, G., Foggi, B., Frattaroli, A. R., Galdenzi, D., Gangale, C., Gasparri, R., Genovesi, P., Gianguzzi, L., Gironi, F., Giusso Del Galdo, G., Gualmini, M., Guarino, R., Lasen, C., Lastrucci, L., Maneli, F., Pasta, S., Paura, B., Perrino, E. V., Petraglia, A., Pirone, G., Poponessi, S., Prisco, I., Puglisi, M., Ravera, S., Sburlino, G., Sciandrello, S., Selvaggi, A., Spada, F., Spampinato, G., Strumia, S., Tomaselli, M., Tomaselli, V., Uzunov, D., Viciani, D., Villani, M., Wagensommer, R. P., Zitti, S.   +67 more
openaire   +3 more sources

A Protocol to Assess the Welfare of Dairy Ewes: From Science to the Field

Small Ruminant Research, 2023
International ...
Jolly, Pierre-Alexandre, Rouyer, Elise, Bru, Laetitia, Marin, Lorie, Meillac, Elise, Foubert, Gabrielle, Roman, Mathilde, Ponter, Andrew, Patout, Olivier, de Paula Reis, Alline   +9 more
openaire   +3 more sources

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source