Results 61 to 70 of about 1,882,825 (268)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Griffiths Scales of Child Development 3rd Edition: normalization for the Brazilian population

Frontiers in Pediatrics
IntroductionChild development must be carefully evaluated, requiring assessment instruments to assess different areas of development. Griffiths Scales of Child Development 3rd Edition (Griffiths III) is used to assess different areas of development in ...
Amanda Tragueta Ferreira-Vasques, Eduardo Pimentel da Rocha, Elizabeth Green, Dionísia Aparecida Cusin Lamônica   +3 more
doaj   +1 more source

Outcomes in patients with acute upper gastrointestinal bleeding following changes to management protocols at an Australian hospital

JGH Open, 2020
Background and Aim Upper gastrointestinal bleeding (UGIB) has a high mortality rate and requires efficient and directed acute management. This project aimed to assess patient outcomes following changes to UGIB management protocols at Northern Hospital ...
Adrianna Papadinas, Joshua Butt
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Sigurnost protokola rutiranja u ad hoc mrežama i mogući napadi u mreži

Vojnotehnički Glasnik, 2013
U članku se opisuju ad hoc mreže, specifične po svojoj mobilnosti, iznenadnoj promeni stanja i samoorganizovanju. Zbog svojih svojstava protokoli rutiranja u ad hoc mrežama moraju biti prilagođeni primenama i zadovoljavati sigurnosne zahteve – tajnost ...
Radiša Radomir Stefanović, Boban Zoran Pavlović   +1 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Treatment Outcome of Kwashiorkor in Children as Per World Health Organization Guideline at Nutrition Stabilization Center Multan, Pakistan

Journal of Islamic International Medical College
Objective: To assess the treatment outcomes and associated factors among children with kwashiorkor (Edematous Severe Acute Malnutrition) at Nutrition Rehabilitation Centre the Children Hospital and The Institute of Child Health, Multan.
Saadia Khan, Reema Arshad, Muhammad Tauseef Sultan, Summera Tabasum, Nazia Batool, Tehseen Ikram
doaj   +1 more source