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Proton functional magnetic resonance spectroscopy in rodents

NMR in Biomedicine, 2020
Proton functional magnetic resonance spectroscopy (1H‐fMRS) in the human brain is able to assess and quantify the metabolic response due to localized brain activity. Currently, 1H‐fMRS of the human brain is complementary to functional magnetic resonance imaging (fMRI) and a recommended technique at high field strengths (>7 T) for the investigation ...
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Proton magnetic resonance spectroscopy in Kennedy disease

Journal of the Neurological Sciences, 2009
The purpose of this study was to investigate the metabolic abnormalities in Kennedy disease (KD) patients using proton magnetic resonance spectroscopy. Five patients with KD showing typical phenotype were compared with eight age-matched, healthy control subjects.
Chieh-Hsun, Lee   +3 more
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Proton Magnetic Resonance Spectroscopy of Hydrocephalic Infants

Pediatric Neurosurgery, 2007
<i>Objective:</i> The authors present the first report evaluating neonates with chronic hydrocephalus using proton magnetic resonance spectroscopy (1H MRS). The goals of the study were (1) to determine absolute brain metabolite concentrations in premature infants and neonates with hydrocephalus and age-matched controls, (2) conduct an ...
Sean A, McNatt   +3 more
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Hemimegalencephaly: Localized Proton Magnetic Resonance Spectroscopy In Vivo

Epilepsia, 1995
Summary: Two children with hemimegalencephaly were examined by magnetic resonance imaging (MRI) and localized proton MR spectroscopy (MRS). In both cases, structural changes in the enlarged hemisphere included pachy‐or polymicrogyria and gliosis of white matter.
Hanefeld, F.   +6 more
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Phenylketonuria: Diffusion Magnetic Resonance Imaging and Proton Magnetic Resonance Spectroscopy

Journal of Computer Assisted Tomography, 2003
Two patients with phenylketonuria are reported with white matter lesions. Diffusion magnetic resonance (MR) imaging revealed restricted diffusion patterns (high signal) on b = 1000 s/mm2 images associated with low apparent diffusion coefficient values ranging between 0.44 x 10-3 mm2/s and 0.56 x 10-3 mm2/s.
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Cerebral Proton Magnetic Resonance Spectroscopy in Rett Syndrome

Neuropediatrics, 1995
Combined MRI/MRS studies were performed in 9 girls with Rett syndrome of different ages. NAA, as marker of neuronal tissue, was found to decrease with increasing age. There was no evidence for a defective energy metabolism. The data point towards a probably secondary degenerative process in the pathogenesis of Rett syndrome.
Hanefeld, F.   +5 more
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Proton Magnetic Resonance Spectroscopy Changes After Antipsychotic Treatment

Current Medicinal Chemistry, 2013
Proton magnetic resonance spectroscopy ((1)H MRS) enables the observation of brain function in vivo. Several brain metabolites can be measured by the means of (1)H MRS: N-acetylaspartate (NAA), choline containing compounds (Cho), myo-inositol (mI) and glutamate (Glu), glutamine (Gln) and GABA (together as Glx complex or separately).
Agata, Szulc   +5 more
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[Proton magnetic resonance spectroscopy (1H-MRS)].

No shinkei geka. Neurological surgery, 2021
Proton magnetic resonance spectroscopy(1H-MRS)is a non-invasive method for evaluating brain function and metabolism. 1H-MRS can quantify low-molecular-weight metabolites in a living brain; it shows their spectra without tracer administration. In this paper, we introduce 1H-MRS and MRS for imaging the distribution of metabolites.
Hironaka, Igarashi   +3 more
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Proton magnetic resonance spectroscopy in pediatric neuroradiology

Pediatric Radiology, 1998
This review reports on recent developments in proton magnetic resonance spectroscopy (MRS) and its potential clinical application in pediatric neuroradiology. An overview of the essential principles of the methodology including pulse sequences and their practical application is provided.
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Proton magnetic resonance spectroscopy during transient global amnesia

Journal of the Neurological Sciences, 1998
There is uncertainty about the etiology of transient global amnesia and none of the pathogenetic hypotheses proposed so far, i.e. transient ischemia, epileptic discharge and spreading depression of cortical electrical activity, is completely satisfactory.
ZORZON, MARINO   +5 more
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