Results 221 to 230 of about 5,053,091 (357)

Proton therapy of cancer: Potential clinical advantages and cost-effectiveness [PDF]

, 2005
Jonas Lundkvist, Mattias Ekman, Suzanne Rehn Ericsson, Bengt Jönsson, Bengt Glimelius   +4 more
openalex   +1 more source

Proton Beam Therapy [PDF]

European Oncology & Haematology, 2018
openaire   +2 more sources

UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis

Advanced Science, EarlyView.
These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang, Lilong Zhang, Beiying Deng, Wanrong Jiang, Tianrui Kuang, Chen Chen, Kailiang Zhao, Qiao Shi, Jun He, Weixing Wang   +9 more
wiley   +1 more source

Proton-pump inhibitor therapy for acetylsalicylic acid associated upper gastrointestinal symptoms, a randomised clinical trial

, 2003
Robert J.F. Laheij, Leo G.M. van Rossum, Jan B.�M.�J. Jansen, Freek W Verheught   +3 more
openalex   +1 more source

Systematic review and meta‐analysis: enhanced efficacy of proton‐pump inhibitor therapy for peptic ulcer bleeding in Asia – a post hoc analysis from the Cochrane Collaboration [PDF]

, 2005
Grigoris I. Leontiadis, Virender K. Sharma, Colin W. Howden   +2 more
openalex   +1 more source

Intensity modulated proton therapy (IMPT) - The future of IMRT for head and neck cancer.

Oral Oncology, 2019
A. Moreno, S. Frank, A. Garden, D. Rosenthal, C. Fuller, G. Gunn, J. Reddy, W. Morrison, T. Williamson, E. Holliday, J. Phan, P. Blanchard   +11 more
semanticscholar   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities. [PDF]

Front Oncol
Horst F, Bodenstein E, Baumann M, Beyreuther E, Bokor J, Enghardt W, Gantz S, Hejzlar M, Kurth F, Meyer M, Pieck S, Richter C, Pawelke J.   +12 more
europepmc   +1 more source

Donut-Shaped High-Dose Configuration for Proton Beam Radiation Therapy [PDF]

, 2005
Hans Rutz, Antony Lomax
openalex   +1 more source

Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

Advanced Science, EarlyView.
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou, Yuwei Wang, Yu Liu, Feipeng Zhu, Ge Gao, Chengjie Li, Pu Ai, Jingying Xu, Junxin Wang, Long Guo, Yuting Guan, Virginia Man‐Yee Lee, Jianjun Chen, Jialin Zheng, Qihui Wu   +14 more
wiley   +1 more source