Results 231 to 240 of about 249,684 (338)

793 Cranial Base Chordomas and Chondrosarcomas: A 12-year Review of 158 Patients Treated with Fractionated Proton Beam Therapy

, 2004
Walter D. Johnson, Lilia Loredo, Roger Grove, Jerry D. Slater   +3 more
openalex   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source

A Tailored Artificial Biocatalyst for Bacterial Endophthalmitis Therapy via Enhanced Ferroptosis‐Like Death

Advanced Science, EarlyView.
A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun, Yingying Jiang, Shibo Zhang, Zhipeng Ding, Lijun Pu, Xinmei Liu, Jun Yang, Xiangkai Zhuge, Jianjun Dai, Yanmin Ju   +9 more
wiley   +1 more source

Comparing methods to improve cone-beam computed tomography for dose calculations in adaptive proton therapy. [PDF]

Phys Imaging Radiat Oncol
Vestergaard CD, Vatterodt N, Elstrøm UV, Jensen K, Nørrevang O, Muren LP, Korreman SS, Taasti VT.   +7 more
europepmc   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

High‐Throughput MicroED for Probing Ion Channel Dynamics

Advanced Science, EarlyView.
High‐throughput MicroED offers a new approach for visualizing ion channel dynamics. This approach reveals NaK’s sodium binding modes and NaK2CNG’s potassium‐induced selectivity filter dilation and gating. By capturing these distinct structures, this work challenges traditional models of ion channel permeation and selectivity. Abstract Ion channels play
Marc J Gallenito, Max TB Clabbers, Jieye Lin, Johan Hattne, Tamir Gonen   +4 more
wiley   +1 more source

Targeting DAMPs by Aspirin Inhibits Head and Neck Cancer Stem Cells and Stimulates Radio-Sensitization to Proton Therapy. [PDF]

Cancers (Basel)
Vasiljevic T, Zapletal E, Tarle M, Bozicevic Mihalic I, Gouasmia S, Provatas G, Vukovic Djerfi K, Müller D, Hat K, Luksic I, Matijevic Glavan T.   +10 more
europepmc   +1 more source

Proton therapy.

RADIOISOTOPES, 1989
openaire   +3 more sources

Dual‐Modular Hydrogel Microparticles with Precision‐Modulation of Inflammatory Microenvironment Dictate Full‐Thickness Cartilage Regeneration for Osteoarthritis Repair

Advanced Science, EarlyView.
Cartilage injury is a prominent pathological hallmark of osteoarthritis. In this study, we developed a two‐modular hydrogel microparticle system wherein HMP‐A effectively targets the damaged area, while HMP‐B forms an efficient connection with HMP‐A on the cartilage surface.
Xinye Chen, Yuanman Yu, Zirui He, Lina Pan, Jing Wang, Changsheng Liu   +5 more
wiley   +1 more source

Polyacrylic Acid-Coated LaB₆ Nanoparticles as Efficient Sensitizers for Binary Proton Therapy. [PDF]

Pharmaceutics
Ryabtseva MS, Filimonova MV, Filimonov AS, Soldatova OV, Shitova AA, Rybachuk VA, Volkova IK, Nikolaev KA, Kosachenko AO, Koryakin SN, Petrunya DS, Kotelnikova PA, Shemyakov AE, Kolmanovich DD, Popov AL, Tikhonowski GV, Popov AA, Timakova AA, Kolobov AV, Deyev SM, Kabashin AV, Zavestovskaya IN.   +21 more
europepmc   +1 more source