Results 241 to 250 of about 5,021,050 (358)
Carbon dots (CDs) has excellent photoluminescence properties. Aggregation plays an important role in both the formation of CDs and their fluorescence, yet is seldom studied in detail. This review aims to fill this knowledge gap. We first discuss how aggregation leads to the formation of different types of CDs, and the impact on morphology, luminescence,
Yi Ru+2 more
wiley +1 more source
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang+9 more
wiley +1 more source
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li+9 more
wiley +1 more source
Error identification and compensation in large manipulators with application in cancer proton therapy [PDF]
Marco Antônio Meggiolaro+2 more
openalex +1 more source
Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC
AP‐1 family members FOS and JUN regulate the malignant phenotype conversion of normal fibroblasts (NFs) to normal‐like cancer‐associated fibroblasts (nCAFs), while transforming growth factor‐β (TGFβ) and interferon‐γ (IFNγ) signals triggers the interconversion between classic myofibroblastic CAFs (myCAFs) and inflammatory CAFs (iCAFs), respectively ...
Mengyu Tao+15 more
wiley +1 more source
Rationale and proposed algorithms for symptom‐based proton pump inhibitor therapy for gastro‐oesophageal reflux disease [PDF]
Peter Bytzer, A. L. Blum
openalex +1 more source
Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao+11 more
wiley +1 more source
Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo+4 more
wiley +1 more source
The molecular recognition of the sugar moiety of GD3 and Gb3 (globotriaosylceramide) derivatives by Siglec‐7 has been thoroughly studied offering insights for cancer diagnostics and therapies. A combination of structural biology techniques, nuclear magnetic resonance (NMR) spectroscopy, physicochemical analysis, and in silico methods suggested that ...
Cristina Di Carluccio+15 more
wiley +1 more source
Proton Radiation and TNF-α/Bax Gene Therapy for Orthotopic C6 Brain Tumor in Wistar Rats [PDF]
Daila S. Gridley+6 more
openalex +1 more source