Results 241 to 250 of about 5,053,091 (357)

Transfer learning for DL-based Synthetic CT after reconstruction algorithm upgrade in a proton therapy clinic. [PDF]

Med Phys
Galapon A, Wagenaar D, Langendijk JA, Both S.   +3 more
europepmc   +1 more source

MAINTENANCE PROTON PUMP INHIBITOR (PPI) THERAPY DECREASES THE INCIDENCE OF ESOPHAGEAL CANCER (CA) AND HIGH GRADE DYSPLASIA (HGD) IN BARRETTʼS AND CHRONIC HEARTBURN

, 2003
Simmy Bank, Ranvir Singh, Anant Indaram, Nakechand Pooran   +3 more
openalex   +1 more source

Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis

Advanced Science, EarlyView.
The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang, Yuxin Zhang, Simo Xia, Lu Chen, Pei Shen, Chi Yang   +5 more
wiley   +1 more source

Proton Therapy in Uveal Melanoma. [PDF]

Cancers (Basel)
Chan AW, Lin H, Yacoub I, Chhabra AM, Choi JI, Simone CB.   +5 more
europepmc   +1 more source

793 Cranial Base Chordomas and Chondrosarcomas: A 12-year Review of 158 Patients Treated with Fractionated Proton Beam Therapy

, 2004
Walter D. Johnson, Lilia Loredo, Roger Grove, Jerry D. Slater   +3 more
openalex   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu, Zhihuang Zheng, Marleen Silke Oswald, Guozhe Cheng, Jun Liu, Qidi Zhai, Ute Kruegel, Michael Schaefer, Holger Gerhardt, Nicole Endlich, Maik Gollasch, Stefan Simm, Dmitry Tsvetkov   +12 more
wiley   +1 more source

Optimizing quality assurance CT schedules during adaptive proton therapy for enhanced patient care. [PDF]

J Appl Clin Med Phys
Biswal NC, Zakhary MJ, Parchur AK, Mogilnay R, Ferris MJ, Nichols EM, Witek ME, Yi B.   +7 more
europepmc   +1 more source

NDRG1‐Driven Lactate Accumulation Promotes Lung Adenocarcinoma Progression Through the Induction of an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu, Hongxia Cheng, Jiacheng Yin, Yuansheng Zheng, Haochun Shi, Binyang Pan, Ming Li, Mengnan Zhao, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Guoshu Bi, Weigang Guo, Lin Wang, Yiwei Huang   +14 more
wiley   +1 more source

Prospectively assessed hypothalamic-pituitary dysfunction after proton therapy in adults with head and neck, skull base and brain tumors. [PDF]

Sci Rep
Bouter J, Azemar N, Vela A, Dutheil P, Lesueur P, Stefan D, Reznik Y, Thariat J.   +7 more
europepmc   +1 more source