Results 261 to 270 of about 266,081 (333)

Evaluating the technical feasibility of biology-guided dose painting in proton therapy. [PDF]

Phys Imaging Radiat Oncol
Brighi C, Parrella G, Morelli L, Molinelli S, Magro G, Lillo S, Iannalfi A, Ciocca M, Imparato S, Waddington DEJ, Keall P, Paganelli C, Orlandi E, Baroni G.   +13 more
europepmc   +1 more source

Proton linac for hospital-based fast neutron therapy and radioisotope production

, 1989
Arlene Lennox, F.R. Hendrickson, D.A. Swenson, R.A. Winje, D. E. Young   +4 more
openalex   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

Advanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos, Xavier Barceló, M. Gabriella Chiariello, Irene Sanz, Amaia Iturrospe, Arantxa Arbe, J. Alberto Ortega, Siewert J. Marrink, Aitziber L. Cortajarena, Zaida Álvarez, Ivan R. Sasselli   +10 more
wiley   +1 more source

Triggered plan adaptation using multi-image optimization for improved robustness in head-and-neck cancer proton therapy. [PDF]

Phys Imaging Radiat Oncol
Vatterodt N, Winey B, Korreman SS.
europepmc   +1 more source

Comparative study of Radiation Therapy of Targets in the Upper Abdomen with Photon- or Scanned Proton-beams

, 2017
Gracinda Mondlane
openalex   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Enhancing proton therapy quality assurance with custom-designed Octopoint phantom and Gafchromic film. [PDF]

J Appl Clin Med Phys
Tang X, Beltran CJ, Furutani KM, Gilson GS, Gustafson J, Herman MG, Ito S, Johnson JE, Kruse JJ, Long KM, Mundy DW, Remmes NB, Tasson AM, Whitaker TJ, Matysiak W, Tryggestad EJ.   +15 more
europepmc   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Correction: Evaluation of the changes in hydrogel spacer volume in patients treated with proton therapy for prostate cancer. [PDF]

BMC Urol
Inoue K, Shinohara M, Saka T, Hirao Y, Shinohara Y, Higashikawa T, Yamamoto M.   +6 more
europepmc   +1 more source

Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

Advanced Science, EarlyView.
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang Huang   +5 more
wiley   +1 more source