Results 51 to 60 of about 5,053,091 (357)

Temporal Lobe Necrosis in Head and Neck Cancer Patients after Proton Therapy to the Skull Base

International Journal of Particle Therapy, 2020
Purpose: To demonstrate temporal lobe necrosis (TLN) rate and clinical/dose-volume factors associated with TLN in radiation-naïve patients with head and neck cancer treated with proton therapy where the field of radiation involved the skull base ...
S. Kitpanit, Anna Lee, K. Pitter, D. Fan, J. Chow, B. Neal, Zhiqiang Han, P. Fox, K. Sine, D. Mah, L. Dunn, E. Sherman, L. Michel, I. Ganly, R. Wong, J. Boyle, Marc A. Cohen, Bhuvanesh Singh, C. Brennan, I. Gavrilovic, V. Hatzoglou, B. O'Malley, K. Zakeri, Yao Yu, Linda Chen, D. Gelblum, J. Kang, S. McBride, C. J. Tsai, N. Riaz, N. Lee   +30 more
semanticscholar   +1 more source

Comparative clinical evaluation of atlas and deep-learning-based auto-segmentation of organ structures in liver cancer

Radiation Oncology, 2019
Background Accurate and standardized descriptions of organs at risk (OARs) are essential in radiation therapy for treatment planning and evaluation. Traditionally, physicians have contoured patient images manually, which, is time-consuming and subject to
Sang Hee Ahn, Adam Unjin Yeo, Kwang Hyeon Kim, Chankyu Kim, Youngmoon Goh, Shinhaeng Cho, Se Byeong Lee, Young Kyung Lim, Haksoo Kim, Dongho Shin, Taeyoon Kim, Tae Hyun Kim, Sang Hee Youn, Eun Sang Oh, Jong Hwi Jeong   +14 more
doaj   +1 more source

Implementation of Monte Carlo based PET verification of ion beam delivery into a TPS

Radiation Medicine and Protection, 2022
Objective: To develop and implement an ion beam teletherapy verification system based upon simulations of induced radioactivity and comparison with patient positron emission tomography (PET) scans.
Pablo Yepes, Zhuangming Shen, Michael F. Moyers, Qianxia Wang, Hongliang Chen, Jie Li, Yongqiang Li, James Lin   +7 more
doaj   +1 more source

The physics of proton therapy

Physics in Medicine and Biology, 2015
The physics of proton therapy has advanced considerably since it was proposed in 1946. Today analytical equations and numerical simulation methods are available to predict and characterize many aspects of proton therapy. This article reviews the basic aspects of the physics of proton therapy, including proton interaction mechanisms, proton transport ...
Rui Zhang, Rui Zhang, Wayne D. Newhauser
openaire   +3 more sources

Proton therapy in clinical practice [PDF]

Chinese Journal of Cancer, 2011
Radiation dose escalation and acceleration improves local control but also increases toxicity. Proton radiation is an emerging therapy for localized cancers that is being sought with increasing frequency by patients. Compared with photon therapy, proton therapy spares more critical structures due to its unique physics.
Joe Y. Chang, Hui Liu
openaire   +3 more sources

Proton therapy for brain tumours in the area of evidence-based medicine.

British Journal of Radiology, 2020
ADVANCES IN KNOWLEDGE This review details the indication of brain tumors for proton therapy and give a list of the open prospective trials for these challenging tumors.
D. Weber, P. Lim, S. Tran, M. Walser, A. Bolsi, U. Kliebsch, J. Beer, B. Bachtiary, T. Lomax, A. Pica   +9 more
semanticscholar   +1 more source

Dosimetric analysis of local failures in skull-base chordoma and chondrosarcoma following pencil beam scanning proton therapy

Radiation Oncology, 2020
Background Despite combined modality treatment involving surgery and radiotherapy, a relevant proportion of skull-base chordoma and chondrosarcoma patients develop a local recurrence (LR).
Lucas Basler, Robert Poel, Christina Schröder, Alessandra Bolsi, Antony Lomax, Stephanie Tanadini-Lang, Matthias Guckenberger, Damien C. Weber   +7 more
doaj   +1 more source

Outcomes and Prognostic Factors for Locally Recurrent Rectal Cancer Treated With Proton Beam Therapy

Advances in Radiation Oncology, 2023
Purpose: Our objective was to report the outcome and prognostic factors for patients with locally recurrent rectal cancer (LRRC) treated with proton beam therapy (PBT) at our institution.
Yoshiaki Takagawa, MD, Motohisa Suzuki, MD, Hisashi Yamaguchi, MD, Ichiro Seto, MD, Yusuke Azami, MD, PhD, Masanori Machida, MD, Kanako Takayama, DDS, PhD, Takuya Tominaga, DDS, Masao Murakami, MD, PhD   +8 more
doaj   +1 more source

First-in-human trial using mixed-reality visualization for patient setup during breast or chest wall radiotherapy

Radiation Oncology
Background The purpose of this study is to assess the feasibility of mixed-reality (MixR) visualization for patient setup in breast and chest wall radiotherapy (RT) by performing a first-in-human clinical trial comparing MixR with a 3-point alignment ...
Perry B. Johnson, Julie Bradley, Samsun Lampotang, Amanda Jackson, David Lizdas, William Johnson, Eric Brooks, Raymond B. Mailhot Vega, Nancy Mendenhall   +8 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source