The Role of Hypofractionation in Proton Therapy
Cancers, 2022 Hypofractionated radiotherapy is an attractive approach for minimizing patient burden and treatment cost. Technological advancements in external beam radiotherapy (EBRT) delivery and image guidance have resulted in improved targeting and conformality of the absorbed dose to the disease and a reduction in dose to healthy tissue.
Alexandre Santos +3 more
openaire +3 more sources
Cancer, 2020 Proton therapy (PT) improves outcomes in patients with nasal cavity (NC) and paranasal sinus (PNS) cancers. Herein, the authors have reported to their knowledge the largest series to date using intensity‐modulated proton therapy (IMPT) in the treatment ...
M. Fan +20 more
semanticscholar +1 more source
Clinical results of proton beam therapy for elderly patients with non-small cell lung cancer
Radiation Oncology, 2018 Background The purpose of the present study was to evaluate retrospectively the efficacy and safety of proton beam therapy for elderly patients (≥80 years of age) with non-small cell lung cancer.
Takashi Ono +9 more
doaj +1 more source
Proton tracking in a high-granularity Digital Tracking Calorimeter for proton CT purposes [PDF]
, 2017 Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient.
Alme, J. +14 more
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Proton versus photon radiation therapy: A clinical review
Frontiers in Oncology, 2023 While proton radiation therapy offers substantially better dose distribution characteristics than photon radiation therapy in certain clinical applications, data demonstrating a quantifiable clinical advantage is still needed for many treatment sites ...
Zhe Chen +3 more
semanticscholar +1 more source
Using thymine-18 for enhancing dose delivery and localizing the Bragg peak in proton-beam therapy [PDF]
arXiv, 2021 Therapeutic protons acting on O18-substituted thymidine increase cytotoxicity in radio-resistant human cancer cells. We consider here the physics behind the irradiation during proton beam therapy and diagnosis using O18-enriched thymine in DNA, with attention to the effect of the presence of thymine-18 on cancer cell death.
arxiv
Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]
, 2014 It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R. +3 more
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Online daily adaptive proton therapy.
British Journal of Radiology, 2020 It is recognised that the use of a single plan calculated on an image acquired some time before the treatment is generally insufficient to accurately represent the daily dose to the target and to the organs at risk. This is particularly true for protons,
F. Albertini +4 more
semanticscholar +1 more source
Current evidence and the potential role of proton beam therapy for hepatocellular carcinoma [PDF]
Clinical and Molecular Hepatology, 2023 Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death, and external beam radiation therapy has emerged as a promising approach for managing HCC.
Sung Uk Lee, Tae Hyun Kim
doaj +1 more source
Proton beam therapy in the management of skull base chordomas: systematic review of indications, outcomes, and implications for neurosurgeons [PDF]
, 2016 BACKGROUND: Chordomas are rare tumours affecting the skull base. There is currently no clear consensus on the post-surgical radiation treatments that should be used after maximal tumour resection.
Choi, D, Matloob, SA, Nasir, HA
core +1 more source