Results 61 to 70 of about 249,684 (338)

A Real-time Image Reconstruction System for Particle Treatment Planning Using Proton Computed Tomography (pCT)

, 2017
Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest.
Coutrakon, George, Duffin, Kirk, Johnson, Robert, Karonis, Nicholas, Ordoñez, Caesar E., Pankuch, Mark, Schulte, Reinhard   +6 more
core   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Dose ratio proton radiography using the proximal side of the Bragg peak [PDF]

, 2015
Purpose: In recent years there has been a movement towards single-detector proton radiography, due to its potential ease of implementation within the clinical environment.
A. Gibson, Akisada, Ball, Bashkirov, Basun, Bentefour, Bentefour, Bohndiek, Boone, Bortfeld, Braccini, Cormack, D. Prieels, Depauw, E. H. Bentefour, Esposito, Esposito, Friedman, G. Royle, Ganschow, Gelover-Reyes, Gottschalk, H.-M. Lu, Hollebeek, Hurley, Hünemohr, Konstantinidis, Lu, Lu, Lu, Meroli, Muraishi, P. J. Doolan, Paganetti, Pemler, Poludniowski, Rinaldi, Rinaldi, Ryu, Schaffner, Schneider, Schneider, Schneider, Schneider, Schulte, Schulte, Seco, Shinoda, Sipala, Stewart, Talamonti, Telsemeyer, Testa, Vanzi, Watts   +54 more
core   +1 more source

Clinical results of proton beam therapy for twenty older patients with esophageal cancer

Radiology and Oncology, 2015
Background. In an aging society, increasing number of older patients are diagnosed with esophageal cancer. The purpose of this study was to assess the clinical efficacy and safety of proton beam therapy for older patients with esophageal cancer.
Ono Takashi, Nakamura Tatsuya, Azami Yusuke, Yamaguchi Hisashi, Hayashi Yuichiro, Suzuki Motohisa, Hatayama Yoshiomi, Tsukiyama Iwao, Hareyama Masato, Kikuchi Yasuhiro, Nemoto Kenji   +10 more
doaj   +1 more source

Proton radiography and tomography with application to proton therapy

The British Journal of Radiology, 2015
Proton radiography and tomography have long promised benefit for proton therapy. Their first suggestion was in the early 1960s and the first published proton radiographs and CT images appeared in the late 1960s and 1970s, respectively. More than just providing anatomical images, proton transmission imaging provides the potential for the more accurate ...
Poludniowski, G, Allinson, NM, Evans, PM
openaire   +4 more sources

Cervical Spinal Cord Magnetization Transfer Ratio and Its Relationship With Clinical Outcomes in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee, Julien Cohen‐Adad, Irene M. Vavasour, Melanie Guenette, Katherine Sawicka, Neda Rashidi‐Ranjbar, Nathan Churchill, Akash Chopra, Adelia Adelia, Pierre‐Louis Benveniste, Anthony Traboulsee, Nathalie Arbour, Fabrizio Giuliani, Larry D. Lynd, Scott B. Patten, Alexandre Prat, Alice Schabas, Penelope Smyth, Roger Tam, Yunyan Zhang, Simon J. Graham, Mojgan Hodaie, Anthony Feinstein, Shannon Kolind, Tom A. Schweizer, Jiwon Oh, CanProCo Study Group   +26 more
wiley   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Proton therapy with a fixed beamline for skull-base chordomas and chondrosarcomas: outcomes and toxicity

Radiation Oncology, 2021
Aim This study presents an analysis (efficacy and toxicity) of outcomes in patients with skull-base chordomas or chondrosarcomas treated with a fixed horizontal pencil proton beam.
Konstantin Gordon, Igor Gulidov, Sergey Koryakin, Daniil Smyk, Tatyana Makeenkova, Danil Gogolin, Olga Lepilina, Olga Golovanova, Alexey Semenov, Sergey Dujenko, Kira Medvedeva, Yuri Mardynsky   +11 more
doaj   +1 more source

3D Printed Ultra‐Fast Plastic Scintillators Based on Perovskite‐Photocurable Polymer Composite

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
The demand for radiation detection is increasing in a number of fields, including high‐energy physics, medical imaging, and homeland security. This study serves to demonstrate the potential for the fabrication of fast perovskite‐based scintillators with complex shapes via stereolithographic additive manufacturing, representing a new path toward the ...
Antonella Giuri, Amal C Chekkallur, Mario Calora, Rosanna Mastria, Loris Martinazzoli, Etiennette Auffray, Sanosh Kunjalukkal Padmanabhan, Sara Carturan, Sandra Moretto, Gianluca Quarta, Lucio Calcagnile, Matteo Polo, Alberto Quaranta, Alfonso Maffezzoli, Anna Paola Caricato, Aurora Rizzo, Carola Esposito Corcione   +16 more
wiley   +1 more source

Proton beam therapy is a safe and feasible treatment for patients with second primary lung cancer after lung resection

Thoracic Cancer, 2019
Background The purpose of the present study was to retrospectively evaluate the safety and efficacy of proton beam therapy (PBT) in patients with second primary lung cancer after lung resection.
Takashi Ono, Tatsuya Nakamura, Yusuke Azami, Motohisa Suzuki, Hitoshi Wada, Yasuhiro Kikuchi, Masao Murakami, Kenji Nemoto   +7 more
doaj   +1 more source