Results 71 to 80 of about 260,677 (342)

Nationwide Characterization of MFN2‐Related CMT in 176 Japanese Patients: Clinical and Genetic Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando, Yujiro Higuchi, Jun‐Hui Yuan, Akiko Yoshimura, Chikashi Yano, Takahiro Hobara, Fumikazu Kojima, Yu Hiramatsu, Satoshi Nozuma, Tomonori Nakamura, Yusuke Sakiyama, Jun Mitsui, Shoji Tsuji, Hiroshi Takashima   +13 more
wiley   +1 more source

Data sets of very large linear feasibility problems solved by projection methods [PDF]

, 2011
We give a link to a page on the Web on which we deposited a set of eight huge Linear Programming (LP) problems for Intensity-Modulated Proton Therapy (IMPT) treatment planning. These huge LP problems were employed in our recent research and we were asked
Chen, Wei
core  

Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study [PDF]

, 2011
Background and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication.
Beecher, Belafsky, Birring, Blondeau, Chang, Corley, Decalmer, DeVault, Dial, Eccles, Eherer, Everett, Faruqi, FitzGerald, Gilard, Gulmez, Hemmink, Herzig, Ing, Irwin, Irwin, Irwin, Irwin, Juurlink, Laheij, Lenglinger, Mastronarde, Morice, Morice, Morice, Morice, Noordzij, Pratter, Rostami-Hodjegan, Shaheen, Vaezi, Vertigan, Wager, Waring, Wo, Yang, Yearsley   +41 more
core   +1 more source

Effect of Nonsteroidal Anti‐Inflammatory Drugs on Sacroiliac Joint Inflammation, as Seen on Magnetic Resonance Imaging, in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones, Alexander N. Bennett, Raj Sengupta, Pedro M. Machado, Helena Marzo‐Ortega, Lorna Aucott, Margaret A. Hall‐Craggs, Timothy J. P. Bray, Alan Bainbridge, Ruaridh M. Gollifer, Gary J. Macfarlane   +10 more
wiley   +1 more source

The grid-dose-spreading algorithm for dose distribution calculation in heavy charged particle radiotherapy [PDF]

, 2007
A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed.
Ahnesjö, Azusa Ishizaki, Bortfeld, Deasy, Endo, Hollmark, Hong, Kanai, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kanematsu, Kohno, Krämer, Langen, Lomax, Mackie, Mackie, Nobuyuki Kanematsu, Noda, Petti, Russell, Schaffner, Sharpe, Shunsuke Yonai, Soukup, Szymanowski, Tsuji, Yan   +29 more
core   +3 more sources

Exploring patients’ profiles associated with the resolution of acute calcium pyrophosphate arthritis treatedwith colchicine and prednisone: post hoc analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Proton-microwave therapy [PDF]

PACS2001. Proceedings of the 2001 Particle Accelerator Conference (Cat. No.01CH37268), 2002
The new method of tumor therapy is proposed: joining up proton (photon) and microwave methods. The combined tumor therapy gives the possibility of simultaneous influence on the albumen molecules (tissue cells) in vivo of RF/microwave and proton (photon) radiation. Such an influence must be made not only synchronous but coherent as well.
M. Ivanyan, G. Oksuzyan
openaire   +2 more sources

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Proton beam therapy is a safe and feasible treatment for patients with second primary lung cancer after lung resection

Thoracic Cancer, 2019
Background The purpose of the present study was to retrospectively evaluate the safety and efficacy of proton beam therapy (PBT) in patients with second primary lung cancer after lung resection.
Takashi Ono, Tatsuya Nakamura, Yusuke Azami, Motohisa Suzuki, Hitoshi Wada, Yasuhiro Kikuchi, Masao Murakami, Kenji Nemoto   +7 more
doaj   +1 more source

Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]

, 2018
The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski, Anna Brożyna, Anna Markiewicz, Bożena Romanowska-Dixon, Ewa Podgórska, Krystyna Urbańska, Martyna Elas, Martyna Śniegocka, Małgorzata Szczygieł, Michał Żmijewski, Mirosława Cichorek, Przemysław Płonka   +11 more
core   +1 more source