Results 71 to 80 of about 168,635 (283)

CO2 reduction with protons and electrons at a boron-based reaction center. [PDF]

, 2019
Borohydrides are widely used reducing agents in chemical synthesis and have emerging energy applications as hydrogen storage materials and reagents for the reduction of CO2. Unfortunately, the high energy cost associated with the multistep preparation of
Essex, Laura A, Harman, W Hill, McSkimming, Alex, Taylor, Jordan W   +3 more
core  

Simulation of weak polyelectrolytes: A comparison between the constant pH and the reaction ensemble method

, 2017
The reaction ensemble and the constant pH method are well-known chemical equilibrium approaches to simulate protonation and deprotonation reactions in classical molecular dynamics and Monte Carlo simulations.
Holm, Christian, Landsgesell, Jonas, Smiatek, Jens   +2 more
core   +1 more source

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]

, 2018
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M., Bethel, Christopher R., Bonomo, Robert A., Giannini, Estefanía, Klinke, Sebastian, Llarrull, Leticia Irene, Mojica, María F., Otero, Lisandro Horacio, Palacios, Antonela Rocio, Taracila, Magdalena A., Vila, Alejandro Jose   +10 more
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Thioacetyl-Terminated Ferrocene-Anthraquinone Conjugates: Synthesis, Photo- and Electrochemical Properties Triggered by Protonation-Induced Intramolecular Electron Transfer

Molecules, 2010
Two thioacetyl-terminated ferrocene-anthraquinone donor-acceptor molecules with different π-electron conjugative units have been synthesized via a series of Stille and Sonagashira reactions.
Masaki Murata, Hiroshi Nishihara, Kosuke Namiki, Takako Fujita, Mio Kondo, Wen-Wei Zhang   +5 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

5-Fluorouracil—Complete Insight into Its Neutral and Ionised Forms

Molecules, 2019
5-Fluorouracil (5FU), a common anti-cancer drug, occurs in four tautomeric forms and possesses two potential sites of both protonation and deprotonation.
Justyna Wielińska, Andrzej Nowacki, Beata Liberek   +2 more
doaj   +1 more source

Time-dependent H2 formation and protonation

, 2009
Methods: The microscopic equations of H2-formation and protonation are integrated numerically over time in such a manner that the overall structures evolve self-consistently under benign conditions. Results: The equilibrium H2 formation timescale in an H
Bakes, Bensch, Chieze, Cox, Crawford, Deshpande, Draine, Federman, Goldsmith, Gry, H. S. Liszt, Jenkins, Jenkins, Jura, Le Petit, Le Teuff, Lee, Liszt, Liszt, Liszt, Liszt, Liszt, Liszt, Liszt, Liszt, Lucas, Lucas, McCall, McCall, McKee, Meyer, Moore, Nash, Rawlings, Savage, Savage, Wannier, Weingartner, Wolfire, Wolfire   +39 more
core   +1 more source

On proton-proton bremsstrahlung [PDF]

Physics Letters B, 1967
Abstract The cross section for proton-proton bremsstrahlung has been calculated for soft photons in a model independent way. Comparison with experiments has been made.
openaire   +1 more source