Toward Imaging Biosensors for Spatial Mapping of Analytes in Macroscopic Specimens
Advanced Sensor Research, Volume 5, Issue 2, February 2026.This perspective provides an overview of imaging biosensors used for spatial mapping of analytes on the surfaces of macroscopic specimens, such as plant and animal tissues. These devices incorporate various detection principles, including colorimetry, fluorometry, bioluminescence, ultrasound‐assisted, electrochemical, and thermometric detection.
Hayelom Dargo Beyene, Pawel L. Urban
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Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy [PDF]
, 2016 Journal Article“The final publication is available at Springer via http://dx.doi.org/10.1007/s10103-012-1188-y"Methyl aminolevulinate photodynamic therapy (MAL-PDT) (a topical treatment used for a number of precancerous skin conditions) utilizes the ...
Allen, James +4 more
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ChemPhysChem, Volume 27, Issue 3, February 2026.Photochemical investigations were coupled with radical detection for quantifying oxidative processes in sea‐surface microlayer (SML) samples. A chemical actinometry approach was employed to measure photon flux in in situ EPR experiments and under solar irradiation.
Daniele Scheres Firak +5 more
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Monitoring the accumulation and dissipation of the photosensitizer protoporphyrin IX during standard dermatological methyl-aminolevulinate photodynamic therapy utilizing non-invasive fluorescence imaging and quantification [PDF]
, 2016 Author's post-print is subject to a Creative Commons Attribution Non-Commercial No Derivatives LicenseBACKGROUND: Dermatological methyl-aminolevulinate photodynamic therapy (MAL-PDT) is utilized to successfully treat dermatological conditions. This study
Campbell, Sandra M. +2 more
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International Journal of Cosmetic Science, Volume 48, Issue 1, Page 186-199, February 2026.Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier +9 more
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Formation of meso, N-diphenylprotoporphyrin IX by an aerobic reaction of phenylhydrazine with oxyhemoglobins. [PDF]
, 2003 Administration of phenylhydrazine to rabbits resulted in the denaturation of hemoglobins in erythrocytes, causing the formation of intracellular precipitates known as Heinz bodies, severe hemolytic anemia, and reticulocytosis.
Abe, Tadashi +8 more
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Food Science and Technology Research, 2007 The formation of zinc protoporphyrin IX (ZnPP) and protoporphyrin IX (PP) in porcine heart mitochondria was investigated by fluorescent spectral analysis. The time-course study at 37°C and pH 5.5 with 100μM ZnCl2 showed a linear formation of ZnPP from oxymyoglobin after a lag-period (9h) at the formation rate of 0.46nmol/h. The formed amount of ZnPP is
Hiroya ISHIKAWA +5 more
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Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane Disintegration
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Zoi Laspa +5 more
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Enhancement of 5-aminolevulinic acid-induced photodynamic therapy by a bioadhesive polymer
Journal of Dental Sciences, 2010 Using a topical formulation of 5-aminolevulinic acid (ALA), a mediated photodynamic therapy (PDT) was developed to treat oral precancerous and cancerous lesions.
Shu-Fang Chang +4 more
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The effects of protoporphyrin IX-induced photodynamic therapy with and without iron chelation on human squamous carcinoma cells cultured under normoxic, hypoxic and hyperoxic conditions. [PDF]
, 2016 BACKGROUND: Photodynamic therapy requires the combined interaction of a photosensitiser, light and oxygen to ablate target tissue. In this study we examined the effect of iron chelation and oxygen environment manipulation on the accumulation of the ...
Allen, James +2 more
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