Results 71 to 80 of about 20,002 (267)
Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane Disintegration
Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Zoi Laspa +5 more
wiley +1 more source
Metal Nanoclusters for Cancer Imaging and Treatment
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
Total Synthesis and Conformational Analysis of Monophenyl Substituted Protoporphyrins. IX
- The total synthesis of meso-monoaryl protoporphyrins ( 1 ) and ( 2 ) using a MacDonald type [2+2] condensation is described. In this method a bisformyl dipyrrylmethane is treated with a biscarboxydipyrrylmethane. Attempts to obtain the δ -meso-monoaryl
G. Buldain +3 more
semanticscholar +1 more source
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding +11 more
wiley +1 more source
Activated neutrophils release extracellular traps (NETs) that promote tumor metastasis. FTP‐NPs are develpoed, a peptidic nanomaterial that binds NE on neutrophil membranes, forming NE‐fibril clusters that deactivate NE and prevent NETs formation. This strategy reduces metastasis and enhances the anti‐tumor immune response by targeting NE subcellular ...
Yichi Chen +13 more
wiley +1 more source
A Growth‐Coupled Evolutionary Strategy Enhances Heme Biosynthesis in Saccharomyces cerevisiae
Graphical Abstract and Lay Summary Introducing a plasmid with a heme‐responsive promoter connected to a growth‐promoting gene into Saccharomyces cerevisiae created a positive feedback loop between intracellular heme levels and cell growth. After 100 h of adaptive evolution, the plasmid was removed, resulting in a mutant strain that exhibited an ...
Seoyoon Bang +3 more
wiley +1 more source
Chairside testing for cariogenic bacteria: current concepts and clinical strategies [PDF]
Modern approaches to dental caries such as STEM (System for Total Environmental Management) are based on a whole-of-patient and whole-of-biofilm approach to the disease.
Tsang, Annetta K. L., Walsh, Laurence J.
core
Cobalt protoporphyrin IX increases endogenous G-CSF and mobilizes HSC and granulocytes to the blood [PDF]
Granulocyte colony-stimulating factor (G-CSF) is used in clinical practice to mobilize cells from the bone marrow to the blood; however, it is not always effective. We show that cobalt protoporphyrin IX (CoPP) increases plasma concentrations of G-CSF,
Bukowska-Straková, Karolina +12 more
core +2 more sources
Protoporphyrin Production of Tetrahymena geleii
SummaryA strain of Tetrahymena geleii W at the end of its rapid phase of growth on solid media in darkness turns red-brown. The main pigment component has been identified as protoporphyrin. A minor component containing protoporphyrin appears to be bound to some fatty material.
M A, RUDZINSKA, S, GRANICK
openaire +2 more sources
Ability of a Local Bacillus cereus DS1 Isolate of Dematallization of Heavy Metals [PDF]
Bacillus cereusDS1 isolate obtained from oil contaminated soil sample, has been isolated in the previous experiments. It was selected for its ability to degrade Nickel protoporphyrin disodium as a model of a heavy metal organic compound .In this research
Qatie, Eman H +4 more
core +2 more sources

