Results 51 to 60 of about 9,190 (204)
Safety of selective IL‐23p19 inhibitors for the treatment of psoriasis
Journal of the European Academy of Dermatology and Venereology, Volume 33, Issue 9, Page 1676-1684, September 2019., 2019 Abstract Psoriasis is a chronic disease that requires long‐term treatment. Consequently, understanding the safety and tolerability of any potential treatment over time is critical to effective prescribing. The biologic agents currently available for the treatment of psoriasis target a number of different inflammatory cytokines involved in psoriasis ...
J.J. Crowley, R.B. Warren, J.C. Cather
wiley +1 more source
Hydrodynamic Modeling of the Interaction of Winds within a Collapsing Turbulent Gas Cloud
Advances in Astronomy, Volume 2015, Issue 1, 2015., 2015 By using the particle‐based code Gadget2, we follow the evolution of a gas giant molecular cloud, in which a set of gas particles representing the wind are created by a Monte Carlo scheme and suddenly move outwards from the cloud’s center. The particles representing the gas cloud initially have a velocity according to a turbulent spectrum built in a ...
Guillermo Arreaga-García +2 more
wiley +1 more source
The Astrophysical Journal, 2023 While dust disks around optically visible, Class II protostars are found to be vertically thin, when and how dust settles to the midplane are unclear. As part of the Atacama Large Millimeter/submillimeter Array large program, Early Planet Formation in ...
Zhe-Yu Daniel Lin +28 more
doaj +1 more source
Physicochemical Constraints on the Abiotic Polymerization of Nucleotides Into RNA
Journal of Geophysical Research: Biogeosciences, Volume 130, Issue 11, November 2025.Abstract One of the key steps in the origin of life is the polymerization of nucleotides into nucleic acids like RNA. We have quantified the energetic impact of temperature, pressure, and composition on the polymerization of nucleotides into RNA using the Gibbs function. These Gibbs energies have been used to calculate the probability that a nucleotide
D. E. LaRowe, J. M. Dick
wiley +1 more source
A Hydrodynamical Model of a Rotating Wind Source and Its Effects on the Collapse of a Rotating Core
Advances in Astronomy, Volume 2015, Issue 1, 2015., 2015 This work presents three‐dimensional hydrodynamical simulations with the fully parallel GAGDET2 code, to model a rotating source that emits wind in order to study the subsequent dynamics of the wind in three independent scenarios. In the first scenario we consider several models of the wind source, which is characterized by a rotation velocity Vrot and
Guillermo Arreaga-Garcia +1 more
wiley +1 more source
Merger Conditions of Population III Protostar Binaries
The Astrophysical Journal, 2023 Massive close binary stars with extremely small separations have been observed, and they are possible progenitors of gravitational-wave sources. The evolution of massive binaries in the protostellar accretion stage is key to understanding their formation
Takanobu Kirihara +3 more
doaj +1 more source
The Herschel Orion Protostar Survey: Luminosity and Envelope Evolution [PDF]
, 2017 The Herschel Orion Protostar Survey obtained well-sampled 1.2–870 μm spectral energy distributions (SEDs) of over 300 protostars in the Orion molecular clouds, home to most of the young stellar objects (YSOs) in the nearest 500 pc. We plot the bolometric
W. J. Fischer +17 more
semanticscholar +1 more source
Rotational Spectroscopy of the Acetone‐Water Complex: Large Amplitude Motions
ChemPhysChem, Volume 25, Issue 21, November 4, 2024.The structure and dynamics of the acetone‐water complex were explored using jet‐cooled rotational spectroscopy and computational chemistry calculations. Our detailed rot‐tunneling analyses of acetone‐H2O and −D2O revealed that the interaction with water disrupts the equivalence of the two methyl rotors, resulting in a significantly lower methyl rotor ...
Jiao Gao +4 more
wiley +1 more source
The Natural Science Underlying Big History
The Scientific World Journal, Volume 2014, Issue 1, 2014., 2014 Nature’s many varied complex systems—including galaxies, stars, planets, life, and society—are islands of order within the increasingly disordered Universe. All organized systems are subject to physical, biological, or cultural evolution, which together comprise the grander interdisciplinary subject of cosmic evolution.
Eric J. Chaisson, Lukas Kratochvil
wiley +1 more source
Formation of Methanol via Fischer‐Tropsch Catalysis by Cosmic Iron Sulphide
ChemPhysChem, Volume 25, Issue 17, September 2, 2024.Periodic quantum mechanical simulations evidence the potentiality to synthesise methanol through a Fischer‐Tropsch mechanism in different astrophysical environments facilitated by the catalytic properties of cosmic FeS grains, which are enhanced by the presence of naturally‐occurring point surface defects.
Berta Martinez‐Bachs +3 more
wiley +1 more source