Results 241 to 250 of about 2,239,555 (323)

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Low risk of transmission of prototype and newly emerged Oropouche virus strains by European Culex pipiens, Aedes albopictus, and Anopheles atroparvus mosquitoes. [PDF]

PLoS Negl Trop Dis
Rosales-Rosas A, Janssens E, Verwimp S, Bartholomeeusen K, Van Dun C, Trappeniers K, Ariën KK, Müller R, Delang L, Brustolin M.   +9 more
europepmc   +1 more source

4D Printing of Self‐Immolative Polymers

Advanced Functional Materials, EarlyView.
The integration of self‐immolative polymers (SIPs) into light‐based 3D printed structures is presented as a new “living” 4D printing strategy. By exploiting their metastability and stimuli‐responsiveness, SIP‐containing printed objects can undergo rapid and triggered degrowth under ambient conditions and subsequent regrowth through polymer ...
Johannes Markhart, Philipp Mainik, Pia S. Klee, Eva Blasco   +3 more
wiley   +1 more source

Understanding preferences for behaviour change support as part of the NHS Health Check: a qualitative study with adults from underserved minoritised ethnic communities. [PDF]

BMJ Open
Griffiths S, Bartlett YK, French DP, McMillan B.   +3 more
europepmc   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Exploring co-design: a systematic review of concepts, processes, models, and frameworks used in public health research. [PDF]

J Public Health (Oxf)
Vargas C, Zorbas C, Longworth GR, Ugalde A, Needham C, Sunil A, Venegas Hargous C, Bennett R, Forrester-Bowling T, Cardoso Richter AP, Allender S.   +10 more
europepmc   +1 more source

001: Prototyping Prototyping

, 2010
openaire   +1 more source

Alkali Ion‐Incorporated HfO2 Dielectrics for Reconfigurable Neuromorphic Computing

Advanced Functional Materials, EarlyView.
This work presents an indium gallium zinc oxide (IGZO) transistor with an alkali cation‐integrated hafnium dioxide (HfO2) dielectric exhibiting synaptic behavior via ion retention. The solution‐based film fabrication strategy overcomes the limitations of atomic layer deposition (ALD) and precursor coating, enabling the control of synaptic retention ...
Seung Yeon Ki, In Cheol Kwak, Seonkwon Kim, Jihyun Kim, Dong Gue Roe, Se‐Jin Kim, Joohoon Kang, Jeong Ho Cho   +7 more
wiley   +1 more source

Smart Steering Wheel Prototype for In-Vehicle Vital Sign Monitoring. [PDF]

Sensors (Basel)
Babusiak B, Smondrk M, Trpis L, Gajdosik T, Madaj R, Gajdac I.   +5 more
europepmc   +1 more source

Prototyping Prototyping: A Preface

, 2010
openaire   +1 more source