Results 51 to 60 of about 51,618 (293)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Using the prototype willingness model to predict doping in sport.
, 2013 To enable preventive measures to be designed, it is important to identify modifiable distal and proximal factors underlying doping behavior. This study investigated aspects of the prototype willingness model in relation to doping. A cross-sectional study
Petróczi, A +11 more
core +1 more source
ReligionsThis essay elucidates Chronicles’ puzzling presentation of Yhwh’s position in the universe. While Chronicles affirms Yhwh’s sole authority, it also describes his presence among other deities.
Kiyoung Kim
doaj +1 more source
Inovasi Matematika, 2021 This study produced a prototype of Riemann's number of teaching materials based on APOS theory. The student activity sheet (LAM) based on APOS theory was designed to help students understand the integral of the subject matter of Riemann quantities.
Maya Saftari, Sariman
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Prototype Mountain Rescue Service Trial [PDF]
, 2010 The purpose of this document is to outline the prototype implementation for the Mountain Rescue service trial. It provides an overall picture of which components have been implemented, how they work together and the methodology of the trial.
Dunmore, Martin +2 more
core
KalbotyraThis paper aims to reveal differences between the competing accusative and locative forms of Lithuanian temporal expressions denoting parts of the day (rytas ‘morning’, diena ‘day’, vakaras ‘evening’, naktis ‘night’).
Nina Kapušová
doaj +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source