Results 41 to 50 of about 396,435 (353)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

What Is It Like to Make a Prototype? Practitioner Reflections on the Intersection of User Experience and Digital Humanities/Social Sciences during the Design and Delivery of the “Getting to Mount Resilience” Prototype

open access: yesInformatics, 2023
The digital humanities and social sciences are critical for addressing societal challenges such as climate change and disaster risk reduction. One way in which the digital humanities and social sciences add value, particularly in an increasingly ...
Ashlin Lee
doaj   +1 more source

Virtual assembly rapid prototyping of near net shapes [PDF]

open access: yes, 2009
Virtual reality (VR) provides another dimension to many engineering applications. Its immersive and interactive nature allows an intuitive approach to study both cognitive activities and performance evaluation.
Corney, Jonathan   +4 more
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Rancang Bangun Aplikasi Computer-based Test (CBT) serta Optimasinya Menggunakan Cache dan Queue Job

open access: yesJurnal Komputer Terapan, 2023
Examinations in schools that still use paper require a great deal of time, effort and money to implement, especially in the activities of printing, duplicating and distributing exam questions to students who will take the exam.
Rahmat Siswanto, Dwi Senjaya A. Morang
doaj   +1 more source

Virtual bloXing - assembly rapid prototyping for near net shapes [PDF]

open access: yes, 2009
Virtual reality (VR) provides another dimension to many engineering applications. Its immersive and interactive nature allows an intuitive approach to study both cognitive activities and performance evaluation.
Corney, Jonathan   +4 more
core  

The Materials Advantage of the SLS Selective Laser Sintering Process [PDF]

open access: yes, 1992
The rapid prototyping market continues to progress in tenns of processes and materials used for the creation of conceptual and functional parts and prototype tooling.
Kimble, Luke L.
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

RaPro: A Novel 5G Rapid Prototyping System Architecture

open access: yes, 2017
We propose a novel fifth-generation (5G) rapid prototyping (RaPro) system architecture by combining FPGA-privileged modules from a software defined radio (or FPGA-coprocessor) and high-level programming language for advanced algorithms from multi-core ...
Gao, Feifei   +6 more
core   +1 more source

Solid Modeling and Stereolithography as a Solid Freeform Fabrication Technique at Texas Instruments Incorporated [PDF]

open access: yes, 1990
Over the past 25 years, the CAE/CAD/CAM industry has developed technological advances that have provided industrial users the ability to increase productivity and decrease the cycle time necessary for product development.
Baumgardner, Owen, Blake, Paul
core   +1 more source

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