Results 91 to 100 of about 205,007 (347)
Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes
Cell Biology International, EarlyView.ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio +6 more
wiley +1 more source
Wellcome Open Research, 2023 We present a genome assembly from cultivated Tetramitus jugosus (Heterolobosea; Schizopyrenida; Vahlkampfiidae). The genome sequence is 26.3 megabases in span. Most of the assembly (99.3%) is scaffolded into 52 chromosomal pseudomolecules.
Cecilia Rad-Menéndez, David H. Green
doaj
Frontiers in Immunology, 2020 Cutaneous Leishmaniasis (CL) affects up to one million people every year and treatments are costly and toxic. The regulation of the host immune response is complex and the knowledge of how CD4+ T cells are activated and maintained during Leishmania ...
Rafael de Freitas e Silva +9 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.A library of novel bisindole derivatives was synthesized through an optimized rapid Suzuki‐Miyaura coupling reaction, utilizing NH2‐unprotected bromobisindole ethanamines and boronic acids with yields up to 93%. The compounds were screened for their activity against L. infantum promastigotes.
Alessandro Buono +8 more
wiley +1 more source
HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage
Frontiers in Immunology, 2018 CD8+ T cells are key players during infection with the malaria parasite Plasmodium berghei ANKA (PbA). While they cannot provide protection against blood-stage parasites, they can cause immunopathology, thus leading to the severe manifestation of ...
Franziska Muscate +7 more
doaj +1 more source
In Vitro Rumen Fermentation and Anti Mastitis Bacterial Activity of Diet Containing Betel Leaf Meal (Piper Betle L.) [PDF]
, 2013 The aims of this experiment was to study the inhibition effect of betel leaf meal (BLM) addition into concentrate diet on mastitis causing bacteria and on rumen fermentation condition.
Evvyernie, D. (D) +2 more
core
The natural alternative: protozoa as cellular models for Legionella infection
Cellular Microbiology, 2014 The severe pneumonia known as Legionnaires' disease occurs following infection by the Gram‐negative bacterium Legionella pneumophila. Normally resident in fresh‐water sources, Legionella are subject to predation by eukaryotic phagocytes such as amoeba ...
C. Hoffmann +2 more
semanticscholar +1 more source
Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives
ChemMedChem, EarlyView.Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi +7 more
wiley +1 more source
The Immortality of the Protozoa [PDF]
Nature, 1907 IN a footnote to p. 42 of Coleridge's “Biographia Literaria” (Bohn's Library) occurs the following statement:—
openaire +3 more sources
Food Safety and Health, EarlyView.This graphical abstract highlights the benefits of genetically modified (GM) foods, including high‐yield crops such as golden rice with enhanced nutrition, GM vaccines, and biofuel production. Advanced analytical methods ensure safety by detecting allergenicity and toxicity, promoting sustainability while addressing environmental impacts and balancing ...
Mohamad Warda +5 more
wiley +1 more source