Results 41 to 50 of about 26,884 (239)

Fatal disseminated Toxoplasma gondii infection in a captive harbour porpoise (Phocoena phocoena) [PDF]

open access: yes, 2015
A 7-year-old female harbour porpoise (Phocoena phocoena), born and held in captivity, suffered from reduced consciousness, imprecise and circling swimming movements and long phases of immobility over a period of 3 weeks.
Herder, V   +8 more
core   +2 more sources

The Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases—Part III: In-Silico Molecular Docking Investigations

open access: yesMolecules, 2016
Malaria, leishmaniasis, Chagas disease, and human African trypanosomiasis continue to cause considerable suffering and death in developing countries. Current treatment options for these parasitic protozoal diseases generally have severe side effects, may
Ifedayo Victor Ogungbe   +1 more
doaj   +1 more source

Anti-protozoal activity and metabolomic analyses of Cichorium intybus L. against Trypanosoma cruzi

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2022
Chagas disease, caused by the protozoa Trypanosoma cruzi, is a potentially life-threatening parasitic zoonosis infecting 6–7 million people worldwide, mainly in Latin America.
Miguel Peña-Espinoza   +7 more
doaj   +1 more source

Echinococcus multilocularis: An emerging pathogen in Hungary and Central Eastern Europe? [PDF]

open access: yes, 2003
Echinococcus multilocularis, the causative agent of human alveolar echinococcosis, is reported for the first time in Red Foxes (Vulpes vulpes) in Hungary.
Egyed, Zsuzsa   +3 more
core   +2 more sources

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon   +12 more
wiley   +1 more source

Antiprotozoal agents – Integration of drug discovery, medicinal chemistry, and advanced computational approaches: An in-depth review

open access: yesThe Microbe
Protozoal diseases have been a global burden for decades, including fatal diseases that can lead to death, particularly in low- and middle-income countries. Many of these diseases are classified under Neglected Tropical Diseases (NTDs).
Aviral Kaushik   +7 more
doaj   +1 more source

Warning against increasing cases of cutaneous leishmaniasis and unavailability of meglumine in Pakistan

open access: yesKhyber Medical University Journal, 2023
Leishmaniasis is the protozoal disease transmitted by sandfly vectors. Leishmaniasis due to the increase in its incidence is becoming a health concern globally.
Sadia Iram   +2 more
doaj   +1 more source

Overview of Genus Prosopis Toxicity Reports and its Beneficial Biomedical Properties [PDF]

open access: yes, 2016
Secondary plant metabolites are regarded as promising sources of plant-protecting substances and they are one of the most important lines of plant defense against pests. The range of cellular targets for these substances is very wide and covers metabolic
Gamarra Luques, Carlos Diego   +3 more
core   +1 more source

Marine silicon for biomedical sustainability

open access: yesBMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han   +3 more
wiley   +1 more source

Detection of Neospora caninum Tachyzoites in Canine Cerebrospinal Fluid [PDF]

open access: yes, 2006
4-year-old female Labrador Retriever was referred to the Veterinary Teaching Hospital of the Autonomous University of Barcelona because of progressive, generalized ataxia and depressed mental status of 5 days' duration.
Añor Torres, Sònia   +4 more
core   +2 more sources

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