Results 21 to 30 of about 17,639 (221)
The MicrobeProtozoal diseases have been a global burden for decades, including fatal diseases that can lead to death, particularly in low- and middle-income countries. Many of these diseases are classified under Neglected Tropical Diseases (NTDs).
Aviral Kaushik +7 more
doaj +1 more source
Using 5-Nitroimidazole Derivatives against Neglected Tropical Protozoan Diseases: Systematic Review
Future PharmacologyNeglected tropical diseases (NTDs) are a significant global health problem. Additionally, anti-protozoan treatments are toxic, and their therapeutic regimens require prolonged treatment times and high concentrations of the drugs.
Micheel M. Vichi-Ramírez +3 more
doaj +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Signal Recognition Particle in Human Diseases
Frontiers in Genetics, 2022 The signal recognition particle (SRP) is a ribonucleoprotein complex with dual functions. It co-translationally targets proteins with a signal sequence to the endoplasmic reticulum (ER) and protects their mRNA from degradation.
Morgana K. Kellogg +2 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar +6 more
wiley +1 more source
Special Issue “Drug Discovery of Antiprotozoal Agents”
PharmaceuticalsProtozoal diseases, such as leishmaniasis, malaria, African sleeping sickness, Chagas disease, amoebiasis, giardiasis, cryptococcosis, and toxoplasmosis (among others), affect and/or have the potential to infect more than one billion people worldwide [...
Francisco Jaime Bezerra Mendonça-Junior
doaj +1 more source
ANTIDotE: anti-tick vaccines to prevent tick-borne diseases in Europe
Parasites & Vectors, 2014 Ixodes ricinus transmits bacterial, protozoal and viral pathogens, causing disease and forming an increasing health concern in Europe. ANTIDotE is an European Commission funded consortium of seven institutes, which aims to identify and characterize tick ...
Hein Sprong +15 more
doaj +1 more source
PREVALENCE OF ECTOCILIATE DISEASES IN CULTURED FRESHWATER FISH AT KAFR EL-SHEIKH GOVERNORATE [PDF]
Kafrelsheikh Veterinary Medical Journal, 2015 A total number of 1600 cultured freshwater fish species; Oreochromis niloticus (O. niloticus), Clarias garepinus (C. garepinus), Ceprinus carpio (common carp) and Mugil cephalus, 100 of each fish species per season with different weights and sizes, were ...
Hend A.M. El-Saftawy +3 more
doaj +1 more source
Protozoal diseases in man [PDF]
The Dublin Journal of Medical Science, 1908 n ...
openaire +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma +6 more
wiley +1 more source