Results 41 to 50 of about 102,782 (296)

The cytoskeleton of protozoan parasites

Current Opinion in Cell Biology, 1996
There are seven processes that require a cytoskeleton in protozoan parasites: nuclear division, cytokinesis, cell shape determination, motility, invasion, flagellar movement of sperm, and intracellular transport.
L G, Tilney, M S, Tilney
openaire   +2 more sources

Investigating the evolution of apoptosis in malaria parasites: the importance of ecology [PDF]

, 2010
Apoptosis is a precisely regulated process of cell death which occurs widely in multicellular organisms and is essential for normal development and immune defences.
Colegrave, Nick, Sarah E Reece, Khan, Shahid M., Reece, Sarah E., Colegrave, N., Pollitt, Laura C., Laura C Pollitt, Nick Colegrave, Reece, S.E., Mohammed Sajid, Pollitt, L.C., Khan, S.M., Sajid, M., Sajid, Mohammed, Shahid M Khan   +14 more
core   +1 more source

Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites

Parasites & Vectors, 2019
Background Developing new antibabesial drugs with a low toxic effect to the animal and with no resistance from Babesia parasites is in urgent demand.
Shimaa Abd El-Salam El-Sayed, Mohamed Abdo Rizk, Naoaki Yokoyama, Ikuo Igarashi   +3 more
doaj   +1 more source

Transient Transfection of the Zoonotic Parasite Babesia microti

Pathogens, 2020
The development of genetic manipulation techniques has been reported in many protozoan parasites over the past few years. However, these techniques have not been established for Babesia microti. Here, we report the first successful transient transfection
Mingming Liu, Shengwei Ji, Mohamed Abdo Rizk, Paul Franck Adjou Moumouni, Eloiza May Galon, Jixu Li, Yongchang Li, Weiqing Zheng, Byamukama Benedicto, Maria Agnes Tumwebaze, Masahito Asada, Xuenan Xuan   +11 more
doaj   +1 more source

Intracellular localization of vitellogenin receptor mRNA and protein during oogenesis of a parthenogenetic tick, Haemaphysalis longicornis

Parasites & Vectors, 2019
Background Vitellogenin (Vg), a key molecule for oocyte development synthesized in the fat body during blood-feeding, is released into the hemolymph and then taken into the oocytes via Vg receptor (VgR) in ticks.
Rika Umemiya-Shirafuji, Ryo Mihara, Kozo Fujisaki, Hiroshi Suzuki   +3 more
doaj   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Experimental Protocol to Toxoplasma gondii Detection in Fresh Goat Milk

Journal of Parasitology Research
Toxoplasma gondii is a zoonotic parasite with global distribution capable of infecting homeothermic animals. Transmission of protozoan to humans includes ingestion of water and raw food contaminated with sporulated oocysts, ingestion of raw or ...
Igor Falco Arruda, Patricia Riddell Millar, Mário Felipe Alvarez Balaro, Thamires Francisco Bonifácio, Raissa Cristina Ferreira Ramos, Maria Regina Reis Amendoeira   +5 more
doaj   +1 more source

Ellagic acid microspheres restrict the growth of Babesia and Theileria in vitro and Babesia microti in vivo

Parasites & Vectors, 2019
Background There are no effective vaccines against Babesia and Theileria parasites; therefore, therapy depends heavily on antiprotozoal drugs. Treatment options for piroplasmosis are limited; thus, the need for new antiprotozoal agents is becoming ...
Amani Magdy Beshbishy, Gaber El-Saber Batiha, Naoaki Yokoyama, Ikuo Igarashi   +3 more
doaj   +1 more source

Toxoplasma gondii Dense Granule Proteins 7, 14, and 15 Are Involved in Modification and Control of the Immune Response Mediated via NF-κB Pathway

Frontiers in Immunology, 2020
Toxoplasma gondii infects almost all warm-blooded animals, including humans, leading to both cellular and humoral immune responses in the host. The virulence of T.
Fumiaki Ihara, Ragab M. Fereig, Ragab M. Fereig, Yuu Himori, Kyohko Kameyama, Kosuke Umeda, Sachi Tanaka, Sachi Tanaka, Rina Ikeda, Masahiro Yamamoto, Masahiro Yamamoto, Yoshifumi Nishikawa   +11 more
doaj   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source