Results 41 to 50 of about 113,128 (245)
Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites
Parasites & Vectors, 2019 Background Developing new antibabesial drugs with a low toxic effect to the animal and with no resistance from Babesia parasites is in urgent demand.
Shimaa Abd El-Salam El-Sayed +3 more
doaj +1 more source
Transient Transfection of the Zoonotic Parasite Babesia microti
Pathogens, 2020 The development of genetic manipulation techniques has been reported in many protozoan parasites over the past few years. However, these techniques have not been established for Babesia microti. Here, we report the first successful transient transfection
Mingming Liu +11 more
doaj +1 more source
Advanced Science, EarlyView.This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang +13 more
wiley +1 more source
Experimental Protocol to Toxoplasma gondii Detection in Fresh Goat Milk
Journal of Parasitology ResearchToxoplasma gondii is a zoonotic parasite with global distribution capable of infecting homeothermic animals. Transmission of protozoan to humans includes ingestion of water and raw food contaminated with sporulated oocysts, ingestion of raw or ...
Igor Falco Arruda +5 more
doaj +1 more source
Morphometric Characterization of Trypanosoma spp. and blood parameters in Pterygoplichthys pardalis (Pisces: Loricariidae) from the Brazilian Amazon [PDF]
Anais da Academia Brasileira de Ciências, 2020 The present study describes Trypanosoma spp. infection and blood parameters in Pterygoplichthys pardalis from the Tapajós River basin in eastern Amazon (Brazil).
LUCICLARA F. DE SOUSA +4 more
doaj +1 more source
Immunity to Protozoan Parasites [PDF]
, 2012 Protozoan parasites cause several diseases, such as Malaria, Leishmaniasis, and Trypanosomiasis, hampering human development worldwide. Many protozoa cause infections that often follow chronic courses, owing to coevolution between parasites and host ...
Hugo D. Lujan +7 more
core +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Periodontology 2000, EarlyView., 2023 Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera +4 more
wiley +1 more source
Parasites & Vectors, 2019 Background There are no effective vaccines against Babesia and Theileria parasites; therefore, therapy depends heavily on antiprotozoal drugs. Treatment options for piroplasmosis are limited; thus, the need for new antiprotozoal agents is becoming ...
Amani Magdy Beshbishy +3 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Phosphatidylcholine (PC) is the most abundant type of phospholipids in eukaryotes constituting ~30% of total lipids in Leishmania. PC synthesis mainly occurs via the choline branch of the Kennedy pathway (choline ⇒ choline-phosphate ⇒ CDP-choline ⇒ PC ...
Samrat Moitra +4 more
doaj +1 more source