Results 111 to 120 of about 7,935 (286)

Nothing is more permanent than the temporary: Understanding protracted displacement and people's own responses TRAFIG Synthesis Report [PDF]

, 2022
Across the world, 16 million refugees and an unknown number of internally displaced persons (IDPs) experience long-lasting conditions of economic precarity, marginalisation, rightlessness and future uncertainty.
Pastore, Ferruccio, Vlastou Dimopoulou, Filyra, Isikozlu, Elvan, Jacobs, Carolien, Christ, Simone, Papatzani, Eva, Ayoub, Fawwaz, Etzold, Benjamin, Al Jarrah, Rasheed, Morosanu, Laura, Al Yakoub, Tamara, Kraler, Albert, Siotou, Alexandra, Hatziprokopiou, Panos, Tobin, Sarah, Buchenau, Ben   +15 more
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Protracted refugee situations and the shrinking durable solutions: could there be a ray of hope in local solutions?

Cogent Social Sciences
The phenomenon of protracted refugee situations and the conditions of refugees living in the same situation have renewed debates on durable refugee solutions.
Samuel Opono, Frank Ahimbisibwe
doaj   +1 more source

Daring to dream of an end to exile in sub-Saharan Africa [PDF]

Forced Migration Review, 2009
Almost 98% of the refugees in Africa today could beconsidered as in protracted refugee situations. We needconcerted efforts to draw as many as possible to a close.
Marjon Kamara
doaj  

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Forced returns and protracted displacement [PDF]

, 2017
Key findings • The needs of unaccompanied migrant young people transitioning to adulthood with precarious or no legal status are absent from UK policy agendas.
Chase, E, Sigona, N
core  

Unfinished business: IDPs in Bosnia and Herzegovina [PDF]

Forced Migration Review, 2009
Fourteen years after the war’s end, renewed national andinternational efforts are needed to complete the work ofsecuring durable solutions for IDPs.
Naveed Hussain, Erin Mooney
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source