Results 111 to 120 of about 7,893 (285)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Daring to dream of an end to exile in sub-Saharan Africa [PDF]
Forced Migration Review, 2009 Almost 98% of the refugees in Africa today could beconsidered as in protracted refugee situations. We needconcerted efforts to draw as many as possible to a close.
Marjon Kamara
doaj
Rights Displaced: The Effects of Long-term Encampment on the Human Rights of Refugees
This paper investigates the use of long-term encampment policies in protracted refugee situations. Unlike most contemporary scholarship on the subject, this work focuses on the human rights of encamped refugees rather than on their rights under ...
Sytnik, Svetlana
core
Forced returns and protracted displacement [PDF]
, 2017 Key findings • The needs of unaccompanied migrant young people transitioning to adulthood with precarious or no legal status are absent from UK policy agendas.
Chase, E, Sigona, N
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Unfinished business: IDPs in Bosnia and Herzegovina [PDF]
Forced Migration Review, 2009 Fourteen years after the war’s end, renewed national andinternational efforts are needed to complete the work ofsecuring durable solutions for IDPs.
Naveed Hussain, Erin Mooney
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Protracted Displacement on the Thai-Burmese Border: The Interrelated Search for Durable Solutions
, 2008 Arts, Education & Law Group, School of Criminology and Criminal JusticeNo Full ...
Banki, Susan, Lang, Hazel
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Social SciencesThis paper addresses the role that communication and media interventions can play in fostering social cohesion among displaced populations in camp settings through a review of both practical and theoretical notions in this area.
Valentina Baú
doaj +1 more source