Results 141 to 150 of about 7,893 (285)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Violent Infrastructure: Protracted Displacement and Housing Injustice in Tskaltubo, Georgia

open access: yes
Internal displacement affects tens of millions of people worldwide due to conflict, violence, and natural disasters. Violent Infrastructure: Protracted Displacement and Housing Injustice in Tskaltubo, Georgia explores the experiences of Internally ...
Moayerian, Neda   +7 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

The inheritance of loss

open access: yesForced Migration Review, 2014
As the civil war in Syria drags on, the scale of displacement continues to increase. While the crisis may be prolonged, refugees and IDPs need support now for their protection, their recovery, and both their immediate and their long-term prospects.
Nigel Fisher
doaj  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Refugee by association

open access: yesForced Migration Review, 2014
Many Syrians, even when they have not been individually singled out, meet the refugee criteria on the grounds of being at risk of persecution because of a perceived association, in the broadest sense, with one of the parties to the conflict.
Blanche Tax
doaj  

Survey of Displaced and Host Households in Four Refugee-Hosting Countries, 2021-2022: Afghanistan, Ethiopia, Jordan, and Kenya

open access: yes
copyright UK Data Service and data collection copyright owner.Data from a large-scale survey carried out with 4,466 displaced and host households in four refugee hosting countries: Afghanistan, Ethiopia, Jordan, and Kenya.

core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

The vulnerability of Palestinian refugees from Syria

open access: yesForced Migration Review, 2014
While Syrian nationals may eventually return to their home country, the future for Palestinians from Syria is increasingly uncertain. Meanwhile they are more vulnerable than, and treated worse than, most other refugees from the Syrian conflict.
Leah Morrison
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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