Results 41 to 50 of about 14,906 (267)
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
Resenha do livro La diffusion numérique des données en SHS: guide des bonnes pratiques éthiques et juridiques, de Véronique Ginoves e Isabelle Gras (org.). Aix-en-Provence: Presses de l’Université de Provence, 2018.
Georgete Medleg Rodrigues
doaj
Sculpteurs-marbriers en Provence
The marble quarry in Trets, in the heart of Provence, has the distinction of being operated by just one family: the Veyriers. Throughout the seventeenth century this dynasty of sculptors and architects worked from Marseille to Genoa for almost a century.
Sandrine Chabre
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Many small and scattered areas of gypsum karst are present in France. They occur in the plains and plateaux (Paris, Lorraine, Provence) as well as in the mountains, especially the Alps.
Chardon M., Nicod J.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Background: Epidemiological data link hard and chlorinated water to atopic dermatitis (AD), but experimental evidence on their effect and on dermocosmetic benefit remains limited. Objectives: We aimed to compare the effects of soft, hard, and chlorinated
Sandrine Bergera Virassamnaik +5 more
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Risk analysis methods are now widely used to inform and help flood protection system managers in their decision making. Identification and characterisation of risk reduction measures are among the main purposes of the risk analysis process.
Beullac B., Tourment R., Gumez F.
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