Results 21 to 30 of about 5,860 (261)

“A NIGHTINGALE CANNOT SING IN A CAGE” – OR CAN IT?

Proverbium, 2021
The international proverb “A nightingale (or other bird) cannot (does not, will not) sing in a cage” is several centuries old—prevalent in English since the eighteenth century—though rebuttals or exceptions to the proverb, both popular and “scientific,”
Chlarles Clay Doyle
doaj  

A Proverb Learned is a Proverb Earned: Proverb Instruction in EFL Classrooms

Eurasian Journal of Applied Linguistics, 2019
This study aims to reveal the situation about proverb instruction in EFL classrooms by seeking future English teachers’ opinions. It is based on the argument that proverbs are an important part of cultural references, figurative, functional and formulaic language; thereby, they lend themselves well to enhancing communicative competence.
CAN DAŞKIN, Nilüfer, HATİPOĞLU, Çiler   +1 more
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

VARIABILITY AND MODIFICATION OF PROVERBS IN THE BULGARIAN MASS MEDIA

Proverbium, 2015
The present research deals with the variability and modification of Bulgarian proverbs in terms of a systematic approach in linguistics. A detailed analysis of proverb usage in the mass media shows that a proverb system undergoes both quantitative and ...
Marina Vager
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A created proverb in a novel becomes broadly used in society: “'Easily in but not easily out', as the lobster said in his lobster pot.”

Crossroads, 2014
C.S. Lewis created several proverbs in his novel The Horse and His Boy. One of these has now become broadly used in English-speaking society. This article cites evidence that this new proverb is now being used in novels, poetry, short stories, blogs, and
Peter Unseth
doaj   +1 more source

The Concept of 'Absurdity' as Reflected in Persian and Arabic Proverbs [PDF]

پژوهش‌های ترجمه در زبان و ادبیات عربی, 2012
"Proverb" is considered as a literary-lingual topic that has outstanding status in Iranian and Arabic culture.Iranian and Arab proverb writers have tried to collect and record proverbs.
Mahmood Mirza'i al-Hosseini
doaj  

Pragmatic Failure in Interpreting Some Proverbs found in SMAN 1 Lubuk Alung

Arbitrer, 2018
Phenomenon of using proverb in academic environment particularly school is usual right now. Not only using Indonesian proverb but also using English proverb, students are interested to apply them.
Yeyep Natrio
doaj   +1 more source