Results 71 to 80 of about 88,357 (278)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim   +4 more
wiley   +1 more source

THE ROLE OF LOCAL LANGUAGE IN NATION’S CHARACTER BUILDING* [PDF]

open access: yes, 2017
There are much complex cultures appeared as the result of “paradigm process in a modern era. New dimensions are fruitful until all experiences and sciences become relative because they tend to be the result of human activity.
Citraresmana, Elvi   +2 more
core  

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter   +5 more
wiley   +1 more source

“HEAVEN IS AS NEAR . . . ”

open access: yesProverbium, 2015
The proverb “We are as near Heaven by sea as by land,” or “The way to Heaven is the same from all places,” or the formula “Heaven is as close to X as to Y” entered the English language toward the end of the fifteenth century. The proverb—or at least the
Charles Clay Doyle
doaj  

Old Saws Repaired [PDF]

open access: yes, 2005
The roots of mangled proverbs as wordplay are historically distant. In Cervantes\u27 classic Don Quixote, one humorous hallmark of Sancho Panchez was his abuse of proverbs; Sancho piled proverb on proverb, using garbled and inflated language, often ...
McManus, Christopher
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

open access: yesAdvanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes   +11 more
wiley   +1 more source

"ROOT, HOG, OR DIE”

open access: yesProverbium, 2014
The American proverb, “root hog or die,” though popular in the early nineteenth century, gained widespread use after President Lincoln used it at the Hampton Roads Conference. Newspapers across the country then published contradictory anecdotal accounts
Barry Shelton
doaj  

John Florio and Shakespeare: Life and Language [PDF]

open access: yes, 2015
Investigations into the link between Shakespeare and John Florio stretch back to the mid eighteenth century when, in his edition of the plays (1747), William Warburton suggested that “by Holofernes is designed a particular character, a pedant and ...
Montini, Donatella
core  

Self‐Assembled Inorganic Nanomembrane Tubes: Rolled‐Up Piezoelectrics for Microacoustic Wave‐Based Actuators and Sensors

open access: yesAdvanced Materials, EarlyView.
This study demonstrates a self‐assembly process to generate free‐standing piezoelectric nanomembranes, forming ultracompact microtubular acoustic wave sensors and actuators. The miniaturized 3D piezoelectric platform reported in this work can be applied in telecommunication, energy harvesting, and acoustofluidics. Moreover, the 3D self‐assembly can add
Raphaël C. L‐M. Doineau   +9 more
wiley   +1 more source

Impairment in Proverb Interpretation as an Executive Function Deficit in Patients with Amnestic Mild Cognitive Impairment and Early Alzheimer’s Disease

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2011
Background/Aims: Proverb interpretation is assumed to reflect executive functions. We hypothesized that proverb interpretation is impaired in patients with amnestic mild cognitive impairment (aMCI) diagnosed as single-domain impairment by common ...
Thomas Leyhe   +3 more
doaj   +1 more source

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