Results 231 to 240 of about 3,116,971 (308)

Correction to "Associations of Vitamin D With GPX4 and Iron Parameters in Chronic Obstructive Pulmonary Disease Patients: A Case-Control Study". [PDF]

Can Respir J
europepmc   +1 more source

Changes of human thermal comfort in Qinghai Province from 1979 to 2024 based on UTCI and its potential tourism impacts. [PDF]

Int J Biometeorol
Wang H, Liu G, Wu F.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

An integrated surveillance in Zhejiang Province: ecological and pathogen survey of vectors and reservoir hosts in 2024. [PDF]

Front Vet Sci
Wang J, Luo M, Liu Q, Li T, Guan Z, Gong Z, Hou J, Sun J, Jiang J.   +8 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Burden and trends of decubitus ulcers in East Asia, 1990-2021, with projections to 2031: a comprehensive analysis of the global burden of disease study. [PDF]

J Health Popul Nutr
Wang L, Liu Z, Zhu X, Zhou Y, Zhao S, Zhao C, Liang H, Zhang J, Gao T, Ding Y.   +9 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Short-term outcomes after hybrid unicompartmental knee arthroplasty: A retrospective cohort study with minimum 3-year follow-up. [PDF]

Medicine (Baltimore)
Zhao Y, Zhou T, Fang Q, Yang Y, Wang P, Li X, Zhao J.   +6 more
europepmc   +1 more source

Five new leafhopper species of <i>Limassolla</i> Dlabola from Thailand and Madagascar (Hemiptera, Cicadellidae, Typhlocybinae). [PDF]

Zookeys
Ran W, Yuan X, Dietrich CH, Su D, Song Y.   +4 more
europepmc   +1 more source

Epidemiology, serovar distribution and spatiotemporal patterns of Salmonella foodborne infections in Liaoning Province, China, 2014-2024: an analysis of sentinel surveillance data. [PDF]

Front Public Health
Yu X, Liu X, Du X, Pei Y, Wang K, Zhang H, Diao W.   +6 more
europepmc   +1 more source