Results 41 to 50 of about 2,058,339 (305)
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Après la Seconde Guerre mondiale, à Besançon, ville moyenne et peu industrialisée de l’est de la France, l’influence du catholicisme reste forte. Ainsi le PCF connaît-il des résultats électoraux plus faibles que la moyenne française et la CGT est-elle ...
Bénédicte Ponçot
doaj +1 more source
Energy Trends: А Chinese Focus [PDF]
Due to the scale and diversity of nature and economic conditions of China the author investigates energy consumption trends of household sector (ResCom) not only in temporal but also in spatial dimension.
Sergei Petrovich Popov
doaj +1 more source
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Dzhagdy-Selemdzinskaya metallogemc zone is shown to be the one of the most productive gold-bearing zones in Priamurskaya province. The placer and ore deposits mined in the area are estimated to be about 350 t of gold, including 293,811 of placer and 57 ...
V. A. Stepanov, A. V. Melnikov
doaj +2 more sources
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
This article explores the characteristics of cultural development in the provinces during the 1950-ies and 1960-ies of the XX century within the context of everyday life in the Soviet Union.
O. D. Popova, M. O. Maslovsky
doaj +1 more source

