Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Changing Gender Relations in Canada: The Rise of Gender-Neutral Forenames. [PDF]
Can Rev SociolGuppy N, Kolpashnikova K.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Research on instrument mix and regional suitability of digital publishing industrial policies: An empirical exploration based on qualitative comparative analysis of fuzzy set. [PDF]
PLoS OneLi S, Lam JFI.
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Efficiency and determinants of science and technology investment in Chinese competitive sports: a provincial DEA-Tobit analysis. [PDF]
Front Sports Act LivingXia R, Lu S, Zhao L.
europepmc +1 more source
Revealing urban residents' ecosystem service preferences in China: Evidence from a nationwide survey. [PDF]
Sci DataWu S, Li D, Liu L, Zhang Z.
europepmc +1 more source
Immunization registries: an essential tool for measles elimination in Canada. [PDF]
CMAJBrown EM, Chambers C, Wilson SE.
europepmc +1 more source
Modeling the Impact of Behavior Changes on Mortality Attributable to Non-communicable Diseases in Canada. [PDF]
J Prev Med Public HealthTanguay L +6 more
europepmc +1 more source
Carbon emission inequality of urban and rural households in China from 2000 to 2020. [PDF]
Sci RepZhou T, Zhou X, Wang Q.
europepmc +1 more source