Impact of LEDGIN treatment during virus production on residual HIV-1 transcription
Background Persistence of latent, replication-competent provirus is the main impediment towards the cure of HIV infection. One of the critical questions concerning HIV latency is the role of integration site selection in HIV expression. Inhibition of the
Gerlinde Vansant +8 more
doaj +1 more source
Specific interaction of TFII‐I with an upstream element on the HIV‐1 LTR regulates induction of latent provirus [PDF]
Tom Malcolm +3 more
openalex +1 more source
An aberrant avian leukosis virus provirus inserted downstream from the chicken c-myc coding sequence in a bursal lymphoma results from intrachromosomal recombination between two proviruses and deletion of cellular DNA [PDF]
Carol Nottenburg +2 more
openalex +1 more source
Reduction of antisense transcription affects bovine leukemia virus replication and oncogenesis.
In sheep infected with bovine leukemia virus (BLV), transcription of structural, enzymatic, and accessory genes is silenced. However, the BLV provirus transcribes a series of non-coding RNAs that remain undetected by the host immune response ...
Thomas Joris +8 more
doaj +1 more source
Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117. [PDF]
A clinical trial was performed to evaluate 3BNC117, a potent anti-HIV-1 antibody, in infected individuals during suppressive antiretroviral therapy and subsequent analytical treatment interruption (ATI).
Barton, John P +20 more
core +1 more source
Tissue-specific expression of human provirus ERV3 mRNA in human placenta: two of the three ERV3 mRNAs contain human cellular sequences [PDF]
Naohiro Kato +6 more
openalex +1 more source
Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr [PDF]
Vicente Planelles +7 more
openalex +1 more source
HTLV-1 Provirus and Mycosis Fungoides [PDF]
S. J Whittaker, L. Luzzatto
openaire +3 more sources
The role of Smarcad1 in retroviral repression in mouse embryonic stem cells
Background Moloney murine leukemia virus (MLV) replication is suppressed in mouse embryonic stem cells (ESCs) by the Trim28-SETDB1 complex. The chromatin remodeler Smarcad1 interacts with Trim28 and was suggested to allow the deposition of the histone ...
Igor Bren +3 more
doaj +1 more source
Quantitation of Human Immunodeficiency Virus Provirus and Circulating Virus: Relationship with Immunologic Parameters [PDF]
Virologic and seroimmunologic parameters were determined in 56 persons infected with human immunodeficiency virus (HIV). The provirus level varied from 10 to 100,000/106 CD4+ lymphocytes, and genomic HIV RNA was detectable in 39 of 56 patients at a ...
Chamot, E. +3 more
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