The baboon endogenous virus genome. II. Provirus sequence variations in baboon cell DNA [PDF]
, 1980 Restriction analysis of the approximately 100 integrated baboon endogenous virus (BaEV) proviruses in baboon cells and tissues has revealed two major sequence variations, both in the gag gene region of the genome.
Maurice Cohen +5 more
openalex +4 more sources
Provirus Activation Plus CD59 Blockage Triggers Antibody-Dependent Complement-Mediated Lysis of Latently HIV-1–Infected Cells [PDF]
Journal of Immunology, 2014 Latently HIV-1–infected cells are recognized as the last barrier toward viral eradication and cure. To purge these cells, we combined a provirus stimulant with a blocker of human CD59, a key member of the regulators of complement activation, to trigger ...
J. Lan +10 more
semanticscholar +3 more sources
People Living With HIV Have More Intact HIV DNA in Circulating CD4+ T Cells if They Have History of Pulmonary Tuberculosis [PDF]
Pathogens and ImmunityBackground: A primary barrier to curing HIV is the HIV reservoir. The leading infectious cause of death worldwide for people living with HIV is tuberculosis (TB), but we do not know how TB impacts the HIV reservoir.
Marc Antoine Jean Juste +15 more
doaj +2 more sources
Retroviral DNA—the silent winner: blood transfusion containing latent feline leukemia provirus causes infection and disease in naïve recipient cats [PDF]
Retrovirology, 2015 The feline leukemia virus (FeLV) is a gamma-retrovirus of domestic cats that was discovered half a century ago. Cats that are infected with FeLV may develop a progressive infection resulting in persistent viremia, immunodeficiency, tumors, anemia and ...
Stefanie Nesina +7 more
semanticscholar +9 more sources
Transcriptional and Epigenetic Regulatory Mechanisms Affecting HTLV-1 Provirus [PDF]
Viruses, 2016 Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus associated with human diseases, such as adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/Tropic spastic paraparesis (HAM/TSP).
P. Miyazato +3 more
semanticscholar +4 more sources
Reduction of antisense transcription affects bovine leukemia virus replication and oncogenesis. [PDF]
PLoS PathogensIn sheep infected with bovine leukemia virus (BLV), transcription of structural, enzymatic, and accessory genes is silenced. However, the BLV provirus transcribes a series of non-coding RNAs that remain undetected by the host immune response ...
Thomas Joris +8 more
doaj +2 more sources
Avian myeloblastosis provirus cloned in a lambda bacteriophage is leukemogenic [PDF]
Journal of Virology, 1982 The avian myeloblastosis virus provirus inserted in a lambda bacteriophage, recombinant clone 11A1-1 (Souza et al., Proc. Natl. Acad. Sci. U.S.A. 77:3004-3008, 1980), was transfected into chicken embryo fibroblasts which had been preinfected with either Rous-associated virus type 61 or the transformation-defective avian sarcoma virus tdB77. Within 4 to
R F Silva +3 more
openalex +4 more sources
A HERV-K provirus in chimpanzees, bonobos and gorillas, but not humans [PDF]
Current Biology, 2001 Evidence from DNA sequencing studies strongly indicated that humans and chimpanzees are more closely related to each other than either is to gorillas [1-4]. However, precise details of the nature of the evolutionary separation of the lineage leading to humans from those leading to the African great apes have remained uncertain.
Madalina Barbulescu +7 more
openalex +4 more sources
Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues
PLoS Biology, 2022 Human endogenous retrovirus (HERV) transcripts are known to be highly expressed in cancers, yet their activity in nondiseased tissue is largely unknown.
A. Burn +3 more
semanticscholar +1 more source
Cells, 2021 Eradication of latent human immunodeficiency virus (HIV) infection is a global health challenge. Reactivation of HIV latency and killing of virus-infected cells, the so-called “kick and kill” or “shock and kill” approaches, are a popular strategy for HIV
Sushant Khanal +4 more
doaj +1 more source