Results 11 to 20 of about 66,750 (285)
Lower HIV provirus levels are associated with more APOBEC3G protein in blood resting memory CD4+ T lymphocytes of controllers in vivo. [PDF]
PLoS ONE, 2013 Immunodeficiency does not progress for prolonged periods in some HLA B57- and/or B27-positive subjects with human immunodeficiency virus type 1 (HIV) infection, even in the absence of antiretroviral therapy (ART).
Mariapia De Pasquale +3 more
doaj +2 more sources
Single-Cell Imaging of HIV-1 Provirus (SCIP) [PDF]
Proceedings of the National Academy of Sciences, 2013 Recent advances in fluorescence microscopy provided tools for the investigation and the analysis of the viral replication steps in the cellular context. In the HIV field, the current visualization systems successfully achieve the fluorescent labeling of the viral envelope and proteins, but not the genome.
Di Primio C +7 more
openaire +4 more sources
Chromatin maturation of the HIV-1 provirus in primary resting CD4+ T cells.
PLoS Pathogens, 2020 Human immunodeficiency virus type 1 (HIV-1) infection is a chronic condition, where viral DNA integrates into the genome. Latently infected cells form a persistent, heterogeneous reservoir that at any time can reactivate the integrated HIV-1.
Birgitta Lindqvist +4 more
doaj +2 more sources
Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines
Nature Communications, 2018 During HIV infection, antiviral therapy can suppress viraemia to undetectable levels and hinder the progression towards AIDS; however the HIV-1 provirus can remain in long-lived CD4+ memory T cells.
Sean Matthew McCauley +6 more
doaj +2 more sources
Development of 5‘ LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals [PDF]
Clinical Epigenetics, 2016 BackgroundHuman immunodeficiency virus type 1 (HIV-1) latency represents the major barrier to virus eradication in infected individuals because cells harboring latent HIV-1 provirus are not affected by current antiretroviral therapy (ART).
Kateřina Trejbalová +9 more
openalex +2 more sources
Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues
PLoS Biology, 2022 Human endogenous retrovirus (HERV) transcripts are known to be highly expressed in cancers, yet their activity in nondiseased tissue is largely unknown.
A. Burn +3 more
semanticscholar +1 more source
Short communication: Relationship between the level of bovine leukemia virus antibody and provirus in blood and milk of cows from a naturally infected herd [PDF]
Journal of Dairy Science, 2016 Juan Pablo Jaworski +8 more
openalex +2 more sources
Frontiers in Immunology, 2023 IntroductionFragmented genomic DNA is constitutively released from dying cells into interstitial fluid in healthy tissue. In cancer, this so-called ‘cell-free’ DNA (cfDNA) released from dying malignant cells encodes cancer-associated mutations.
Thomas Joris +9 more
doaj +1 more source
Viruses, 2023 Feline leukemia virus (FeLV) is a cosmopolitan gammaretrovirus that causes lifelong infections and fatal diseases, including leukemias, lymphomas, immunodeficiencies, and anemias, in domestic and wild felids.
Garrick M. Moll +2 more
doaj +1 more source
Viruses, 2023 Modern HIV-1 treatment effectively suppresses viral amplification in people living with HIV. However, the persistence of HIV-1 DNA as proviruses integrated into the human genome remains the main barrier to achieving a cure.
Johannes C. Botha +12 more
doaj +1 more source