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Characterization of novel human endogenous retrovirus structures on chromosomes 6 and 7. [PDF]
Front GenetPasternack N, Paulsen O, Nath A.
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Nature, 2000
Retroviruses incorporate themselves into a host genome in the form of a provirus, and can be passed on to the host's offspring. Evidence now emerges that one such provirus has been subverted to benefit of humans and other mammals that have a placenta — its protein product, called syncitin, may play an essential part in placental formation.
Jonathan P. Stoye, John M Coffin
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Retroviruses incorporate themselves into a host genome in the form of a provirus, and can be passed on to the host's offspring. Evidence now emerges that one such provirus has been subverted to benefit of humans and other mammals that have a placenta — its protein product, called syncitin, may play an essential part in placental formation.
Jonathan P. Stoye, John M Coffin
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Science, 1976
I have discussed the observations and experiments that led to the formulation and establishment of the provirus hypothesis and the DNA provirus hypothesis, which includes RNA-directed DNA synthesis for the formation of the provirus. I have also discussed some aspects of the present status of our knowledge of the mechanism of formation of the ...
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I have discussed the observations and experiments that led to the formulation and establishment of the provirus hypothesis and the DNA provirus hypothesis, which includes RNA-directed DNA synthesis for the formation of the provirus. I have also discussed some aspects of the present status of our knowledge of the mechanism of formation of the ...
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Cell, 1981
Integration of retroviral DNA appears to occur randomly in host genomes, suggesting that retroviruses can act as insertion mutagens. We have confirmed this prediction by showing that the nontransforming retrovirus, Moloney murine leukemia virus (M-MuLV), can insert its provirus within the selectable target provided by a single provirus in a clonal rat ...
H E, Varmus, N, Quintrell, S, Ortiz
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Integration of retroviral DNA appears to occur randomly in host genomes, suggesting that retroviruses can act as insertion mutagens. We have confirmed this prediction by showing that the nontransforming retrovirus, Moloney murine leukemia virus (M-MuLV), can insert its provirus within the selectable target provided by a single provirus in a clonal rat ...
H E, Varmus, N, Quintrell, S, Ortiz
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Revue d'histoire des sciences, 1994
RÉSUMÉ. — Nous nous proposons de retracer l'histoire du concept de prophage et de montrer son extension à celle du concept d'épisome et de provirus. Cette histoire se confond avec celle de la lysogénie, c'est-à-dire celle des relations d'un virus — à l'un de ses stades — à son hôte.
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RÉSUMÉ. — Nous nous proposons de retracer l'histoire du concept de prophage et de montrer son extension à celle du concept d'épisome et de provirus. Cette histoire se confond avec celle de la lysogénie, c'est-à-dire celle des relations d'un virus — à l'un de ses stades — à son hôte.
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A physical map of caprine arthritis-encephalitis provirus
Virology, 1984Terminally redundant linear proviral DNA of approximately 9.5 kb was the major unintegrated species recovered in the Hirt supernatant fraction of caprine synovial membrane cells infected with strain 75-G63 caprine arthritis-encephalitis virus. A physical map based on the cleavage sites of 13 restriction endonucleases was deduced for this proviral DNA.
S M, Roberson, W P, Cheevers
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Chromosome integration domain for bovine leukemia provirus in tumors
Journal of Virology, 1983The 3'-end host-virus junction fragments from two bovine leukemia virus (BLV)-induced lymphoid tumors (tumors 15-4 and 1351), each containing a single provirus, were used as probes to detect large restriction fragments flanking these proviruses. The DNAs from 28 other independent BLV-induced tumors were checked by Southern analysis of their restriction
R, Kettmann +5 more
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