Results 61 to 70 of about 66,750 (285)

Heparanase, a host gene that potently restricts retrovirus transcription

mBio
Heparanase (HPSE) is a heterodimeric β-D-glucuronidase that is critical in mammalian cells for the enzymatic cleavage of membrane-associated heparan sulfate moieties.
Brandon Waxman, Kyle Salka, Uddhav Timilsina, Supawadee Umthong, Deepak Shukla, Spyridon Stavrou   +5 more
doaj   +1 more source

Ovine progressive pneumonia provirus levels are unaffected by the prion 171R allele in an Idaho sheep flock

Genetics Selection Evolution, 2009
Selective breeding of sheep for arginine (R) at prion gene (PRNP) codon 171 confers resistance to classical scrapie. However, other effects of 171R selection are uncertain.
Herrmann-Hoesing Lynn M, Harrington Robert D, White Stephen N, O'Rourke Katherine I, Knowles Donald P   +4 more
doaj   +1 more source

Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines

Mobile DNA, 2020
Background The cell-surface attachment protein (Env) of the HERV-K(HML-2) lineage of endogenous retroviruses is a potentially attractive tumour-associated antigen for anti-cancer immunotherapy.
Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin, Robert Belshaw   +10 more
doaj   +1 more source

Baboon endogenous virus genome: Molecular cloning and structural characterization of nondefective viral genomes from DNA of a baboon cell strain [PDF]

, 1981
Several heterogeneities in the baboon endogenous virus (BaEV) genomes that are present in the DNA of normal baboon tissues and the baboon cell strain BEF-3 have been described previously.
Cohen, Maurice, Davidson, Norman, Gilden, Raymond V., McAllister, Robert M., Nicolson, Margery O., O'Connell, Catherine, Rein, Alan, Shure, Mavis, Stephens, Robert M.   +8 more
core   +1 more source

The baboon endogenous virus genome. II. Provirus sequence variations in baboon cell DNA [PDF]

, 1980
Restriction analysis of the approximately 100 integrated baboon endogenous virus (BaEV) proviruses in baboon cells and tissues has revealed two major sequence variations, both in the gag gene region of the genome.
Cohen, Maurice, Davidson, Norman, Gilden, Raymond V., McAllister, Robert M., Nicolson, Margery O., Stephens, Robert M.   +5 more
core   +1 more source

Promoter expression of HERV-K (HML-2) provirus-derived sequences is related to LTR sequence variation and polymorphic transcription factor binding sites

Retrovirology, 2018
Increased transcription of the human endogenous retrovirus group HERV-K (HML-2) is often seen during disease. Although the mechanism of its tissue-specific activation is unclear, research shows that LTR CpG hypomethylation alone is not sufficient to ...
M. Montesion, Zachary H. Williams, Ravi P. Subramanian, C. Kuperwasser, J. Coffin   +4 more
semanticscholar   +1 more source

Epigenetic changes around the pX region and spontaneous HTLV-1 transcription are CTCF-independent [version 2; referees: 2 approved]

Wellcome Open Research, 2018
Background: The human retrovirus HTLV-1 inserts the viral complementary DNA of 9 kb into the host genome. Both plus- and minus-strands of the provirus are transcribed, respectively from the 5′ and 3′ long terminal repeats (LTR). Plus-strand expression is
Michi Miura, Paola Miyazato, Yorifumi Satou, Yuetsu Tanaka, Charles R.M. Bangham   +4 more
doaj   +1 more source

Quantification of unintegrated HIV-1 DNA at the single cell level in vivo. [PDF]

PLoS ONE, 2012
In the nucleus of HIV-1 infected cells, unintegrated HIV-1 DNA molecules exist in the form of one and two LTR circles and linear molecules with degraded extremities.
Rodolphe Suspène, Andreas Meyerhans
doaj   +1 more source

Clinical Aspects of Feline Retroviruses: A Review [PDF]

, 2012
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses with global impact on the health of domestic cats. The two viruses differ in their potential to cause disease.
Ackley, Anderson, Barlough, Barnett, Barr, Beatty, Beatty, Beatty, Bishop, Bishop, Brightman, Brown, Callanan, Callanan, Carmichael, Choi, Cotter, Cotter, Cotter, Court, Cullen, Day, Dean, Diehl, Dow, Ellis, English, Essex, Fleming, Flynn, Francis, Garg, Gunn-Moore, Hara, Hardy, Harrus, Heit, Hoffmann-Fezer, Hofmann-Lehmann, Holznagel, Hoover, Hoover, Hutson, Jackson, Jarrett, Johnson, Joshi, Katrin Hartmann, Kipar, Kohn, Kubes, Lauring, Levy, Levy, Levy, Liang, Linenberger, Lott-Stolz, Matsumoto, Mitchell, Mizuno, Mizuno, Mizuno, Mortola, Mortola, Novotney, O'Connor, Ohno, Ohno, Overbaugh, Pedersen, Pedersen, Phillips, Phipps, Podell, Podell, Pool, Power, Prospero-Garcia, Quackenbush, Reinacher, Rickard, Ritchey, Rohn, Schrenzel, Sellon, Sellon, Sheets, Shelton, Shelton, Shimojima, Shimojima, Stiles, Taniguchi, Tompkins, Torten, Tsatsanis, Willett, Willett, Zaccaro, Zhao   +100 more
core   +3 more sources

Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms

Retrovirology, 2005
Background Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) after a long latent period. Among accessory genes encoded by HTLV-I, the tax gene is thought to play a central role in oncogenesis.
Mueller Nancy, Maeda Michiyuki, Yasunaga Jun-ichirou, Nosaka Kisato, Taniguchi Yuko, Okayama Akihiko, Matsuoka Masao   +6 more
doaj   +1 more source