Results 151 to 160 of about 2,528,395 (280)

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Selective Catalytic Production of Urea: Unravelling the Pairwise Competition on p‐d Alloy Catalysts

open access: yesAdvanced Science, EarlyView.
Unraveling the complicated competition in urea electrosynthesis, this work investigates asymmetric p‐d alloys. We establish two stage‐specific descriptors, Anchoring Affinity and Coupling Propensity, to elegantly quantify thermodynamic bottlenecks.
Qingchao Fang   +6 more
wiley   +1 more source

Austin Papers: Series IV, 1834-1835 (2 of 2)

open access: yes
Copy of transcript for a letter from The Provisional Government of Texas to the Mexican People, in which the Provisional Government argues that the tenants of Mexican liberalism and the cause of Texas independence are ...

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A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

open access: yesAdvanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng   +12 more
wiley   +1 more source

NRS-18570 | Visitors book [Selly Oak Provisional School / Tenterden Provisional School [III] Tenterden Public School [II]]

open access: yes
<p>The Public Instruction Act, 1866 authorised special religious instruction by visiting clergymen and their delegates (Public Schools Act, 1866, s.19), and regulations under the Act authorised members of the public to visit schools during &lsquo ...

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