Results 111 to 120 of about 1,043,240 (311)
Recent Changes to Canada's Financial Sector Legislation [PDF]
Significant legislative developments have occurred in Canada's financial services sector over the past decade. This article chronicles those developments and gives an overview of the key provisions contained in Bill C-8, the legislation to reform the ...
Fred Daniel
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Constitutional and Legal Protection of the Right in Personal Life
دراسات: علوم الشريعة والقانون, 2020 The right to private life is one of the fundamental constitutional rights inherent to the natural person in his human capacity as a public asset and is the backbone of personal freedom, a fundamental pillar of human rights and public freedoms, and the ...
Fiasal Shatnawi +2 more
doaj
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Хабаршы. Заң сериясы, 2016 This article discusses the features of compensation of harm, caused to life and health of the tourist, according to the legislation of the Republic of Kazakhstan. The correlation of norms of the legislation on tourist activity with the General provisions
Dochshanova A.S., Smatlayev N.B.
doaj
Capital adequacy regulation of financial conglomerates in the European Union [PDF]
, 2010 Over the past few decades, changes in market conditions such as globalisation and deregulation of financial markets as well as product innovation and technical advancements have induced financial institutions to expand their business activities beyond ...
Yoo, Y. Emilie
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Design and fabrication of the Mini-Brayton Recuperator (MBR) [PDF]
Development of a recuperator for a 2.0 kW closed Brayton space power system is described. The plate-fin heat exchanger is fabricated entirely from Hastelloy X and is designed for 10 years continuous operation at 1000 K (1300 F) with a Xenon-helium ...
Graves, R. +2 more
core +1 more source
Nothing to fear? Equal representation in the Scottish parliament and the threat of legal challenge [PDF]
, 1999 No abstract ...
Busby, Nicole, Smith, Rhona
core