Results 221 to 230 of about 58,193 (283)

Diabetes Type 2: Circulating Phosphatidylserine-Expressing Platelets Regulate Whole Blood Agonist-Evoked Platelet Activity In Vitro. [PDF]

TH Open
Järemo P, Oweling M, Edvardsson M.
europepmc   +1 more source

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

Successful Treatment of Hamstring Tendinopathy in a Nonathlete with Ultrasound-Guided Injection to the Ischial Tuberosity: A Case Report. [PDF]

Reports (MDPI)
Watanabe K, Akizawa C, Sawada R, Chinzei M, Moriyama K.   +4 more
europepmc   +1 more source

Negative Predictive Value of Allergologic Work-Up with Iodinated Contrast Media in 'Real-Life' Practice. [PDF]

J Clin Med
Specjalski K, Iwaszko I, Typiak D, Juszkiewicz D, Szablewska W, Skotnicki M, Le N, Powietrzyński M, Strukowski A, Śledzik J, Chełmińska M, Niedoszytko M.   +11 more
europepmc   +1 more source

A proposal of an echocardiography-based pathway for the diagnosis and management of angina with no obstructive coronary arteries: a state-of-the-art review: Advancing Targeted Therapy and Prognosis Through Endotype Identification. [PDF]

Eur Heart J Imaging Methods Pract
Kardos A, Bussmann B, George M, De Maria GL, Gaibazzi N.   +4 more
europepmc   +1 more source

The Central Role of Echocardiography in Mavacamten Therapy for Obstructive Hypertrophic Cardiomyopathy: A Comprehensive Review. [PDF]

Cardiol Res Pract
Nizam A, Antoun I, Hodson L, Ng GA, Dhutia H.   +4 more
europepmc   +1 more source

Phenotypic Characterization of Unclassified Pulmonary Hypertension. [PDF]

Circ Heart Fail
Reddy YNV, Frantz RP, Egbe AC, Miranda WR, Asokan AK, Hassoun PM, Hemnes AR, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Finet JE, Mukherjee M, Tang WHW, Nair KS, Borlaug BA.   +17 more
europepmc   +1 more source