Results 81 to 90 of about 3,416,307 (297)

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

open access: yesAdvanced Science, EarlyView.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao   +11 more
wiley   +1 more source

Laparoscopic gastrectomy and transvaginal specimen extraction in a morbidly obese patient with gastric cancer

open access: yes, 2016
Laparoscopic gastrectomy for cancer has some significant postoperative benefits over open surgery with similar oncologic outcomes. This procedure is more popular in the Far East countries where obesity is not a serious public health problem.
Karagül, Servet   +2 more
core   +1 more source

Gastric remnant carcinoma : histochemical and immunohistochemical profile [PDF]

open access: yes, 2004
Includes bibliographical references (leaves 52-65).Gastric remnant carcinoma (GRC) is a gastric cancer that develops in gastric remnant more than five years after resection for benign disease. GRC comprises 1 %-9% of all gastric cancers.
Elazzabi, Tawfik
core   +1 more source

Analysis of the short- and long-term outcomes of membrane anatomy-guided laparoscopic spleen-preserving circumferential splenic hilar lymph node dissection for treating advanced proximal gastric cancer

open access: yesWorld Journal of Surgical Oncology, 2019
Objective To investigate the short- and long-term efficacy of membrane anatomy-guided laparoscopic spleen-preserving circumferential splenic hilar lymph node dissection for the treatment of advanced proximal gastric cancer.
Yanchang Xu   +6 more
doaj   +1 more source

Individualized proximal margin for early gastric cancer patients

open access: yesWorld Journal of Gastroenterology, 2014
There is no robust evidence to define a safe proximal margin by distance for early gastric cancer (EGC). The discussion on resection margin should not only focus on the oncologic safety, but also the postgastrectomy quality of life. The distance 1-10 mm is only acceptable for those endoscopic treatment fit EGC patients.
Xin-Zu, Chen   +2 more
openaire   +2 more sources

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun   +16 more
wiley   +1 more source

Clinical Implementation of Precision Medicine in Gastric Cancer [PDF]

open access: yes, 2019
Gastric cancer (GC) is one of the deadliest malignancies in the world. Currently, clinical treatment decisions are mostly made based on the extent of the tumor and its anatomy, such as tumor-node-metastasis staging.
정재호
core   +1 more source

Gastric Cancer: Past, Present and Future

open access: yesCanadian Journal of Gastroenterology, 2001
Gastric cancer remains a major cause of cancer mortality in the world. However, in the past 10 decades, the view of gastric cancer has been changing. This includes the unexplained decline in the incidence of the cancer, the proximal shift of the cancer ...
Annie On-On Chan   +2 more
doaj   +1 more source

Comparison of the overall survival of proximal and distal gastric cancer after gastrectomy: a systematic review and meta-analysis

open access: yesWorld Journal of Surgical Oncology, 2021
Background The aim of this study was to investigate the overall survival (OS) between proximal gastric cancer (PG) and distal gastric cancer (DG) patients after gastrectomy. Methods Articles on the prognostic study of PG and DG patients after gastrectomy
Jiaming Xue   +5 more
doaj   +1 more source

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