Results 111 to 120 of about 1,611,351 (254)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Skin and Proximity Effect Calculation of a System of Rectangular Conductors Using the Proper Generalized Decomposition Technique

Energies
This paper presents the application of a numerical approach known as proper generalized decomposition (PGD) to calculate the per-unit length (PUL) ac resistance of rectangular conductors.
Barzan Tabei, Aniruddha M. Gole, Behzad Kordi   +2 more
doaj   +1 more source

Giant thermoelectric effects in a proximity-coupled superconductor–ferromagnet device

New Journal of Physics, 2014
The usually negligibly small thermoelectric effects in superconducting heterostructures can be boosted dramatically due to the simultaneous effect of spin splitting and spin filtering. Building on an idea of our earlier work (Machon et al 2013 Phys. Rev.
P Machon, M Eschrig, W Belzig
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

He II Proximity Effect and the Lifetime of Quasars

, 2016
The lifetime of quasars is fundamental for understanding the growth of supermassive black holes, and is an important ingredient in models of the reionization of the intergalactic medium.
Hennawi, J. F., Khrykin, I. S., McQuinn, M., Worseck, G.   +3 more
core   +1 more source

Assessing the Aging Effect on Ti/Au Bilayers for Transition-Edge Sensor (TES) Detectors

Sensors
Transition-edge sensor (TES) microcalorimeters are advanced cryogenic detectors that use a superconducting film for particle or photon detection. We are establishing a new production line for TES detectors to serve as cryogenic anticoincidence (i.e ...
Maria Gambelli, Matteo D’Andrea, Rita Asquini, Alessio Buzzin, Claudio Macculi, Guido Torrioli, Sara Cibella   +6 more
doaj   +1 more source

Structural and Superconducting Proximity Effect of SnPb Bimetallic Nanoalloys. [PDF]

Nanomaterials (Basel), 2022
Gandhi AC, Manjunatha K, Chan TS, Wu SY.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Improvement of YX42° Cut LiTaO₃ SAW Filters with Optical Proximity Effect Correction Method. [PDF]

Micromachines (Basel), 2023
Luo P, Zou Y, Yang X, Li J, Huang X, Zhou J, Han X, Liu Y, Liu Y, Wu T.   +9 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source