Results 121 to 130 of about 1,457,511 (283)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Decoding THz‐Driven Dynamic Fingerprints of Ferroelectric Nanotwin Networks

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Ultrafast polarization dynamics in ferroelectrics are of considerable interest for high‐speed tunable dielectrics and electro‐optics. Extended domain wall networks formed in ferroelectric twin nanodomains can support collective dynamics in the terahertz regime but require techniques that track polarization and strain evolution driven by ...
Xiaojiang Li   +20 more
wiley   +1 more source

A Comparative Study on Early‐Stage Icing Evaluation Techniques for Passive Ice Protection Systems

open access: yesAdvanced Materials Interfaces, EarlyView.
This study addresses the lack of standardized methodologies for evaluating the early‐stage icing performance of passive ice protection systems. A unified experimental protocol is proposed and applied to representative hydrophilic and hydrophobic surfaces under controlled conditions.
Lorenzo Facco   +4 more
wiley   +1 more source

Calibration by Proxy

open access: yesAnalytical Chemistry
Calibration by Proxy (CbPx) is a matrix-matched calibration method that utilizes multiple internal standard species to build a calibration curve. The technique requires only two solutions: solution 1 containing a sample solution and a suite of internal standards at known concentrations, and solution 2 identical to solution 1, plus an aliquot of a ...
Willis B. Jones   +2 more
openaire   +2 more sources

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

open access: yesAdvanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner   +10 more
wiley   +1 more source

Passive Shape‐Adaptive Fluidic Interface for Enhanced Skin‐Sensor Coupling in Wearable Devices

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a passive fluidic interface for wearable biosensors that adapts to static and dynamic body shape changes to maintain consistent skin contact. Flexible, fluid‐filled pouches redistribute pressure from high‐load areas to regions requiring improved contact, enhancing signal quality and comfort in a compact, low‐energy design for ...
Natalia Sanchez‐Tamayo   +6 more
wiley   +1 more source

Linking Device Performance to Nanoscale Photoactivation of Grain Boundaries in 2D Hybrid Halide Perovskites

open access: yesAdvanced Materials Technologies, EarlyView.
The opto‐electronic response of polycrystalline (PEA)2PbBr4 thin films is investigated by correlating macroscopic photodetector performance with nanoscale mapping techniques. Grain boundary density is systematically tuned through crystallization control and linked to device responsivity.
Camilla Bordoni   +10 more
wiley   +1 more source

Frecuencia y duración de sequías en la cuenca de México de fines del siglo XVI a mediados del XIX

open access: yesInvestigaciones Geográficas, 2002
El estudio del clima en su comportamiento secular por medio del análisis sistemático de las fuentes documentales se inscribe entre los denominados proxy-records, registros utilizados con el fin de reconocer el comportamiento climático en periodos ...
Gustavo Gerardo Garza Merodio
doaj  

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