Results 71 to 80 of about 121,501 (296)

US policy in the Horn of Africa: aboulia or proxy intervention?

Review of African Political Economy, 1977
Among the many questions raised by the dramatic events in the Horn of Africa none is more important or more misunderstood than that of the role played by the USA, and by its various Middle Eastern allies, in the region. The Carter Administration claims that it has avoided direct involvement in the conflicts and has berated the Soviet Union and Cuba for
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos, Lindsay A. Jibb, Gary Rodin   +2 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Applying the Transtheoretical Model to Health Care Proxy Completion [PDF]

, 2011
Background. For many, an important health decision is whether or not to document end-of-life wishes using an advance directive (e.g., health care proxy).
Mary Ann Jezewski, Jongwon Lee, Mary Ann Meeker, Loralee Sessanna, Yow-Wu Bill Wu, Deborah S. Finnell   +5 more
core   +1 more source

Proxy-based modeling of indoor air pollution exposure and nonlinear health patterns in biomass-dependent households using machine learning

Frontiers in Public Health
This study seeks to address critical gaps in household air pollution (HAP) exposure assessment in low- and middle-income settings by applying a proxy-based exposure reconstruction framework supported by machine learning to develop an exploratory proxy ...
Adeyinka Odebode, Olusiji Lasekan, Ayorinde Ogundele, Héctor H. Silva, Boluwatife Adigun   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Systematic review to identify proxy indicators to quantify the impact of eHealth tools on maternal and neonatal health outcomes in low-income and middle-income countries including Delphi consensus [PDF]

, 2018
Objective To identify interventions that could serve as reliable proxy indicators to measure eHealth impact on maternal and neonatal outcomes. Design Systematic review and Delphi study. Methods We searched PubMed, Embase and Cochrane from January 1990 to
Geissbuhler, Antoine, Hounga, Lothaire, Perrin Franck, Caroline   +2 more
core   +1 more source

Psychometric testing of a set of patient-reported instruments to assess healthcare interventions for autistic adults [PDF]

, 2020
Interventions to improve healthcare for autistic adults are greatly needed. To evaluate such interventions, researchers often use surveys to collect data from autistic adults (or sometimes, their supporters), but few survey measures have been tested for ...
Croen, Lisa A., Lee, Junghee, Raymaker, Dora M., Maslak, Joelle, Scharer, Mirah, Croen, Lisa A, Urbanowicz, Anna, Nicolaidis, Christina, Zhen, Kelly Y, Kapp, Steven K., Raymaker, Dora M, Kapp, Steven K, Zhen, Kelly Y.   +12 more
core   +1 more source