Results 171 to 180 of about 1,131 (250)

Energy metabolism, adenosine, and glutamate signaling reprogramming by decanoic acid in Glut1 disorder syndrome

open access: yesEpilepsia Open, EarlyView.
Abstract Glut1 deficiency syndrome (Glut1DS) leads to neurological and cognitive symptoms and is primarily treated using carbohydrate‐restricted ketogenic diets. However, a recent clinical trial of a less restrictive, non‐ketogenic, medium chain triglyceride (MCT) diet with a high decanoic acid content suggests efficacy in Glut1DS treatment.
Erwann Pain   +10 more
wiley   +1 more source

An Unfolding Story: AlphaFold's View on Protein Flexibility

open access: yesHelvetica Chimica Acta, EarlyView.
AlphaFold confidence measures allow for detailed proteome‐wide characterization of protein flexibility. All flexibility measures increased substantially in the evolutionary transition from prokaryota to eukaryota. ABSTRACT The AlphaFold confidence measures are related to conformation distribution of the protein.
Gunnar Jeschke
wiley   +1 more source

Equity by Design: A Positive Organizational Scholarship Approach to Human Resource‐Artificial Intelligence Systems Design

open access: yesHuman Resource Management, EarlyView.
ABSTRACT In today's polarized sociopolitical climate, diversity, equity, and inclusion (DEI) efforts increasingly face backlash, with equity in particular becoming marginalized in both scholarly and practitioner discourse despite its central importance for ensuring fair allocation of opportunities and resources across the employee lifecycle.
Tiffany M. Trzebiatowski   +2 more
wiley   +1 more source

Artificial intelligence for personalized multiple micronutrient supplementation in maternal health

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Maternal undernutrition and micronutrient deficiencies remain pervasive, contributing to adverse pregnancy outcomes and long‐term health risks for mothers and offspring. Multiple micronutrient supplementation (MMS) during pregnancy has demonstrated benefits, including reduced risks of low birth weight, small‐for‐gestational‐age births, and ...
Gabriel Davis Jones   +9 more
wiley   +1 more source

Two stable gut microbiome guilds predict liver tumor class and treatment responses

open access: yesiMeta, EarlyView.
Gut microbiome alterations are linked to hepatocellular carcinoma (HCC), yet taxon‐based biomarkers often lack reproducibility. Using shotgun metagenomics from 120 resectable HCC (MT) and 76 benign hepatic tumor controls (BT), we reconstructed a stable interaction‐based Two Competing Guilds model (HCC‐TCG) comprising 142 genomes organized into two ...
Yang Liu   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy